Ultrasound-mediated optical tomography (UOT) is a hybrid technique that is able to combine the high penetration depth and high spatial resolution of ultrasound imaging to overcome the limits imposed by optical scattering for deep tissue optical sensing and imaging. It has been proposed as a method to detect blood concentrations, oxygenation and metabolism at depth in tissue for the detection of...

PET imagery is a valuable oncology tool for characterizing lesions and assessing lesion response to therapy. These assessments require accurate delineation of the lesion. This is a challenging task for clinicians due to small tumor sizes, blurred boundaries from the large point-spread-function and respiratory motion, inhomogeneous uptake, and nearby high uptake regions. These aspects have led t...

Radiation dose calculation using models of the human anatomy has been a subject of great interest to radiation protection, medical imaging, and radiotherapy. However, early pioneers of this field did not foresee the exponential growth of research activity as observed today. This review article walks the reader through the history of the research and development in this field of study which star...

Abstract Phantoms are essential tools for the development and characterization of Magnetic Particle Imaging (MPI), an imaging technique that can quantitatively map spatial distribution magnetic nanoparticles (MNP). The objective this study was to develop validate a modular MPI phantom kit with high versatility platform-independent quality assurance assembling defined geometries in MPI. It shown...

When vacancies are filled, the job ads often remain, creating phantom vacancies. Older listings more likely represent phantoms. We assume seekers direct their search based on listing age. Forming a match with an age-a vacancy creates probability β and generates externality affecting aged older. Thus, decreases match's Relative to efficient behavior, overapply younger listings. calibrate using U...

A hybrid optical device that uses a multimode fiber coupled to a tunable light source for illumination and a 2.4-mm photodiode for detection in contact with the tissue surface is developed as a first step toward our goal of developing a cost-effective, miniature spectral imaging device to map tissue optical properties in vivo. This device coupled with an inverse Monte Carlo model of reflectance...

In this work, a first-of-its-kind fully integrated tri-modality system that combines fluorescence, diffuse optical and x-ray tomography (FT/DOT/XCT) into the same setting is presented. The purpose of this system is to perform quantitative fluorescence tomography using multi-modality imaging approach. XCT anatomical information is used as structural priori while optical background heterogeneity ...

The paper discusses fabrication of homogenous and heterogeneous breast phantoms to simulate the dielectric properties of human breast over the microwave frequency range from 0.5GHz to 13.5GHz. The breast phantoms have stable mechanical configuration and dielectric properties suitable for microwave imaging experiments particularly ultra-wideband microwave imaging for breast cancer detection.

We present a method to make phantoms of coronary arteries for intravascular optical coherence tomography (IV-OCT). The phantoms provide a calibrated OCT response similar to the layered structure of arteries. The optical properties of each layer are achieved with specific concentrations of alumina and carbon black in a silicone matrix. This composition insures high durability and also approximat...

An evaluation of two anthropomorphic breast phantoms, which have been designed for quality assurance and dose verification of radiotherapy treatment of breast cancer patients, is presented. These phantoms are identical in terms of their dimensions and shape, and composed of several layers of either Plastic Water or tissue-equivalent material. Both water- and tissue-equivalent phantoms include l...