Introduction: shorter hospital stay and less pain in comparison to open surgery considered to be major benefits for laparoscopic cholecystectomy. We compared the effect of intraperitoneal hydrocortisone plus bupivacaine with bupivacaine alone on pain relief following laparoscopic cholecystectomy.  Methods: Sixty two patients participated in this double-blind, randomized clinical trial. Pati...

Daun, Jane M., and Joseph G. Cannon. Macrophage migration inhibitory factor antagonizes hydrocortisone-induced increases in cytosolic IkBa. Am J Physiol Regulatory Integrative Comp Physiol 279: R1043–R1049, 2000.—Macrophage migration inhibitory factor (MIF) is an inflammatory cytokine secreted by several cell types, including mononuclear and pituitary cells. It has also been shown to counteract...

49 HYDROCORTISONE IMPROVED HAEMODYNAMICS AND FLUID REQUIREMENT IN SURVIVING BUT NOT NONSURVIVING OF SEVERELY BURNED PATIENTS The administration of hydrocortisone can lead to a reduction of catecholamines and improved outcome in septic patients. However, no data exist regarding the use of hydrocortisone in burn patients although, in such patients, the reduction of vasopressors may be even more c...

We present 7 adults atopic asthmatics that were referred due to repeatedly relapsing asthma requiring oral courses of prednisolone. All were steroid responsive yet steroid dependant and were screened for adrenal insufficiency after changes to inhaled therapy and other standard antiasthma treatments failed to improve the situation. All were deemed to be compliant. 4 used longterm intranasal ster...

The influence of the gonads and adrenals on tumor growth was studied with SMA mice bearing solid Ehrlich tumors which have been produced by subcutaneous injection of ascitic Ehrlich tumor cells. It was found that the tumor growth was stimulated by the testes and inhibited by the ovaries and also by the administration of hydrocortisone acetate. The inhibitive effect of the adrenocortical hormone...

The effect of ambient temperature and air flow on the radiometric measurement of experimental arthritis in rabbit knee joints has been studied. Temperature changes due to inflammation in such joints could be detected up to 70 days after induction of the arthritis by the use of radiometry. The method has been used to quantitate the anti-inflammatory activity of intra-articularly injected cortiso...