Introduction: SARS-CoV-2 is the name of zoonosis caused a new disease, called COVID-19. The long persistence complaints after initial infection “Post-Acute Consequences Infection” (PASC). Purpose: current prospective study was undertaken to determine whether in-hospital and post-discharge intake three different molecules: Hydroxychloroquine (HCQ), Rosuvastatin Melatonin leads reduction in compl...

I n recent years the expectation of benefit of treatment of rheumatoid arthritis (RA) has evolved. Remission, as defined by the disease activity score (table 1), is now a goal for many clinicians. To achieve this it is standard practice to institute disease modifying antirheumatic drug (DMARD) treatment early in the disease course and to use combination DMARD treatment when single drugs prove i...

Introduction: The SARS-CoV-2 global pandemic has resulted in a universal search for potential treatments of Coronavirus Disease 2019 (COVID-19). Initial reports the therapeutic chloroquine (CQ) and hydroxychloroquine (HCQ) early non-randomized non-controlled studies were followed by subsequent trials refuting such properties. use CQ HCQ diseases, as rheumatoid arthritis (RA) systemic lupus eryt...

Objectives: In this study, we compared the clinical outcomes and effects of treatments on laboratory parameters between patients who were treated with favipiravir (FAV) or hydroxychloroquine plus azithromycin (HCQ/AZ) for COVID-19 pneumonia in non-Intensive Care Unit (non-ICU) patients.
 Methods: We collected data 260 moderate severe hospitalized wards March 20, 2020, September 30, 2020 re...

Background: To employ optical coherence tomography angiography (OCTA) to evaluate the effects of hydroxychloroquine (HCQ) on superficial capillary plexus (SCP) and deep retinal (DCP) in patients affected by rheumatoid arthritis (RA). Methods: Patients with recent diagnosis “definite RA”, based 2010 Rheumatoid Arthritis Classification Criteria, were included a prospective, observational imaging ...

Background/Aim: The common cardiac toxicities of hydroxychloroquine (HCQ) and azithromycin (AZ) are not well defined in COVID-19 patients. Index electrophysiological balance (iCEB) is used as a novel risk marker for drug-induced arrhythmias. purpose this study was to evaluate ventricular repolarization using iCEB other conventional ECG parameters such the end electrocardiographic T wave (Tp-e) ...

The anti-malarial hydroxychloroquine (HCQ) is a common treatment for cicatricial alopecias (CA). Serious adverse events include prolonged QT interval, ventricular arrythmias and irreversible retinopathy. There limited literature on the incidence of in CA patients taking HCQ. A retrospective analysis was performed 60 patients, mean age years, prescribed Alopecia diagnoses included lichen planopi...

Background: Hydroxychloroquine (HCQ) is an extensively used drug in immune-mediated diseases (IMID). Despite its general safety, HCQ can cause serious toxicity such as heart conduction disorders. Atrioventricular block (AVB) underrecognized adverse effect that potentially significant morbidity and mortality. Objectives: To study incidence, presentation, characteristics of HCQ-induced AVB IMID. ...

OBJECTIVE The purpose of this study is to compare the incidence of congenital defects, spontaneous abortions, number of live births, fetal death and pre-maturity in women with autoimmune diseases taking HCQ during pregnancy. METHODS The authors searched MEDLINE, Cochrane data base, Ovid-Currents Clinical Medicine, Ovid-Embase:Drugs and Pharmacology, EBSCO, Web of Science, and SCOPUS using the...

Since the beginning of COVID-19 pandemic, Hydroxychloroquine is being prescribed by doctors all over world for treatment as well prevention with varying results. As we know damage in severe disease occurs mainly via immunological mechanism. There an assumption that HCQ has immunomodulatory property and thus may have a beneficial role disease. In this retrospective study, describe our experience...