Wharton, B. A., Gough, G., Williams, A., Kitts, S., and Pennock, C. A. (1972). Archives of Disease in Childhood, 47,74. Urinary total hydroxyproline: creatinine ratio. Range of normal, and clinical application in British children. The total hydroxyproline: creatinine ratio has been determined in random samples of urine collected from 1577 normal Bristol children and from children with hypothyro...

This study was designed to determine the effects of angiotensin II type 1 (AT(1)) receptor inhibition on coronary hemodynamics and ventricular mass and hydroxyproline content and the additive effects of angiotensin II type 2 (AT(2)) receptor inhibition in spontaneously hypertensive rats (SHR). The selective AT(1) receptor antagonist candesartan (10 mg/kg per day) was administered alone or in co...

To determine the myocardial response to prolonged pressure-loading and unloading, kittens weighing 0.8-1.2 kg underwent pulmonary artery banding, which initially elevated right ventricular (RV) systolic pressure by 10-15 mm Hg. 52 and 76 wk later; RV weight/body weight had increased by approximately 80%. Total RV hydroxyproline had increased significantly, whereas hydroxyproline concentration w...

OBJECTIVE The β-glucans are long-chain polymers of glucose, which comprise the fungal cell wall, stimulate cells of the innate immune system, enhance disturbed epithelization, and have antioxidant effects. Oxidative stress has been implicated in the pathogenesis of bleomycin-induced lung fibrosis and various antioxidant agents have been studied for prevention and treatment of the disease. In th...

The advancement of liposculpturing and fascial flaps in reconstructive surgery has renewed interest in the superficial fascia of abdomen. Its histological and biochemical composition may play a vital role in maintaining strength and elasticity of the fascia. Hence, study of abdominal fascia for the elastic, collagen, and hydroxyproline contents is desirable to understand asymmetrical bulges and...

1. A tissue culture method was devised in which suspensions of osteoblasts, obtained directly from frontal bones of fowl embryos, were grown in a fluid, fibrin-free medium. 2. Maximum growth of the tissue, as measured by dry weight, with the formation of collagen protein, based on the estimation of hydroxyproline, was obtained in periods of up to 6 days. 3. Appreciable amounts of protein-bound ...

The paper discusses the relationship of juvenile dysmenorrhea with connective tissue dysplasia, which biochemical marker is hydroxyproline, and magnesium level in blood serum depending on hormonal profile during the second phase of the menstrual cycle. Study showed that in young woman with dysmenorrhea and phenomena of connective tissue dysplasia hydroxyproline level in urine was increased; it ...