The careful clinical characterization of patients with genetic forms of severe hypercholesterolemia has played a critical role in the historic linkage of hypercholesterolemia to atherosclerosis. Elucidation of gene defects that cause severe hypercholesterolemia has provided molecular entrées into the biosynthetic and regulatory pathways that produce and eliminate cholesterol and has led to the ...

background: the purpose of this study was to explore any gender-related differences in prevalence of and condition-associ­ated factors related to non-alcoholic fatty liver disease (nafld) amongst police population in taipei, taiwan. methods: we studied a total of 1016 healthy adults with police work (972 males and 44 females) voluntarily admitted to physical check-up between january 2006 and de...

The diagnosis of familial hypercholesterolemia by genetic testing is hampered by its cost and effectiveness [1] in many parts of the world including Africa. Familial Hypercholesterolemia (FH) is a common cause of premature cardiovascular disease and is often undiagnosed in young people [2]. The principal metabolic causes of atherosclerosis include hyperlipidemia, hypertension, obesity, insulin ...