نتایج جستجو برای: hypercoagulable state

تعداد نتایج: 857680  

Journal: :Archives of Internal Medicine 2001

2014
Marcella CA Müller Kirsten Balvers Jan M Binnekade Nicola Curry Simon Stanworth Christine Gaarder Knut M Kolstadbraaten Claire Rourke Karim Brohi J Carel Goslings Nicole P Juffermans

INTRODUCTION Data on the incidence of a hypercoagulable state in trauma, as measured by thromboelastometry (ROTEM), is limited and the prognostic value of hypercoagulability after trauma on outcome is unclear. We aimed to determine the incidence of hypercoagulability after trauma, and to assess whether early hypercoagulability has prognostic value on the occurrence of multiple organ failure (MO...

Journal: :British journal of anaesthesia 2004
R I P Dornan

Antiphospholipid syndrome is probably the most common acquired hypercoagulable state, but information on perioperative management is sparse. Minor alterations in anticoagulant therapy, infection, or a surgical insult may trigger widespread thrombosis. The perioperative course of a 31-yr-old woman with primary anticardiolipin antiphospholipid antibody syndrome requiring a mitral valve replacemen...

Journal: :Circulation 2000
G Y Lip A D Blann

Despite advances in pharmacology that have led to increasingly effective antihypertensive drug treatments, the precise pathophysiological mechanisms of hypertension and its complications are still poorly understood. Increasing clinical and laboratory evidence suggests that hypertension per se may confer a prothrombotic or hypercoagulable state.1 This may explain in part why, despite exposure of...

Journal: :Blood 2004
Benjamin Brenner

Pregnancy is a hypercoagulable state with an increased thrombotic risk throughout gestation and the postpartum period. Women with thrombophilia may have a further increased risk of placental vascular complications, including pregnancy loss, preeclampsia, intrauterine growth restriction, and placental abruption. Preliminary data suggest that maternal antithrombotic prophylaxis may result in impr...

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