CONTEXT Ovarian dysfunction is classically categorized on the basis of cycle history, FSH, and estradiol levels. Novel ovarian markers may provide a more direct insight into follicular quantity in hypergonadotropic women. OBJECTIVE The objective of the study was to investigate the distribution of novel ovarian markers in young hypergonadotropic women as compared with normogonadotropic regular...

INTRODUCTION In patients with Y-chromosome in the karyotype, partial gonadal dysgenesis and disorders of male reproductive sex organs development are usually resected in childhood because of the high risk of germ cell tumours (GCT). In patients with Y-chromosome, complete gonadal dysgenesis and female genitalia gonadectomy is performed markedly later. However, due to the relatively low number o...

A 33-year-old male presented to the Chiba University Hospital with the main complaint of right flank pain. Bilateral vas deferens were not palpable. Hormonal examination revealed hypergonadotropic hypogonadism and cytogenetic studies a 47, XXY karyotype. The significance of the association of this karyotype with the absence of vas deferens is discussed. Hideki Fuse, MD, Department of Urology, S...

BACKGROUND Hypergonadotropic hypoestrogenic infertility is the most burdensome complication for females suffering from classic galactosemia. In contrast, male gonadal function seems less affected. The underlying mechanism is not understood and several pathogenic mechanisms have been proposed. Timing of the lesion, prenatal or chronic post-natal, or a combination of both are not yet clear. MET...

background: kallmann syndrome (kal s) is an isolated form of hypogonadotrophic hypogonadism in combination with a defect in smell sensation. depending on the genetic form of the disease, a number of non-reproductive, non-olfactory abnormalities may also be existent. in the present report, we describe a male with kal s associated with hearing loss, and the successful treatment of his sexual and ...

BACKGROUND Male hypogonadism is defined as 'inadequate gonadal function, manifested by deficiency in gametogenesis and/or secretion of gonadal hormones'. Signs and symptoms of hypogonadism depend primarily on the age of onset. It can be classified according to the site primarily involved: the gonads, the hypothalamus, or the pituitary gland. The objective this study was to determine the present...

Hypogonadism is common in clinical practice but is frequently unrecognized and underdiagnosed. The common causes of male hypogonadism vary with the age of presentation. The overall prevalence of male hypogonadism based upon low serum total testosterone levels is high and increases with age. There are many pitfalls in making the diagnosis of male hypogonadism. First, male hypogonadism is sometim...

conclusions chronic hypothyroidism and hypogonadism is not an issue in aneurysmal sah patients results serum prolactin was raised in 17.80% (13/73) and fsh, lh and testosterone levels were reduced in 12.32% (9/73) of patients in the acute phase at admission. after 9 months follow-up, serum prolactin normalized in all except one patient and in all the males, testosterone level increased signific...

OBJECTIVE To define frequency and risk factors of abnormalities in growth, puberty, thyroid function, and bone and carbohydrate metabolisms in children and adolescents with sickle cell disease (SCD). MATERIALS AND METHODS Endocrine problems including short stature, puberty and thyroid disorders, and carbohydrate and bone metabolisms in 50 Turkish children and adolescents with SCD were evaluat...