AIM To investigate the distribution of DNA microsatellite instability (MSI) in a series of hyperplastic polyps, serrated adenomas, and mixed polyps of the colorectum. METHODS DNA was extracted from samples of 73 colorectal polyps comprising tubular adenomas (23), hyperplastic polyps (21), serrated adenomas (17), and mixed polyps (12). The presence of MSI was investigated at six loci: MYCL, D2...

A patient is described who had severe hyperplastic gastropathy as the presenting manifestation of systemic lupus erythematosus (SLE). Aggressive immunosuppressive therapy with systemic corticosteroids and immunoglobulins resulted in complete remission of lupus, and a prompt clinical and radiological regression of hyperplastic gastropathy. Hyperplastic gastropathy is an uncommon gastric illness,...

Introduction. Hyperplastic diseases of the female reproductive system are localized in second place after infectious diseases, and take first by severity. It is known that certain phytonutrients have a chemoprotective effect on organs system. The purpose this review to evaluate potential protective glucosinolates their derivatives isolated from cruciferous plants organs. Material methods. A sys...

Three hundred and thirty six forensic necropsy specimens of large bowel were examined in order to identify subject related variables that independently predicted the following adenoma characteristics: presence, size (largest), multiplicity and high grade dysplasia. The variables were age, gender, body mass index, race (European origin versus Maori/Polynesian) and presence of hyperplastic (metap...

AIM Colorectal cancer has been described in association with hyperplastic polyposis but the mechanism underlying this observation is unknown. The aim of this study was to characterise foci of dysplasia developing in the polyps of subjects with hyperplastic polyposis on the basis of DNA microsatellite status and expression of the DNA mismatch repair proteins hMLH1, hMSH2, and hMSH6. MATERIALS ...

Colorectal adenomas and possibly some hyperplastic polyps are precursors of colorectal cancer. Tobacco use is associated in epidemiologic studies with these polyps, although links between smoking and colorectal cancer are less consistent. To characterize the role of tobacco in early colorectal carcinogenesis, we compared tobacco use among 4,383 subjects with histologically verified benign (hype...

case presentation a 13-year-old boy, in the case presented in this article, had 15 unerupted teeth, each associated with hyperplastic pericoronal tissue. conclusions the purpose of this article is to report an example of this entity and describe the histopathologic characteristics that helps diagnose and treat such condition in the most appropriate manner. introduction pathologic changes may oc...

background: gingival overgrowth is a common side-effect of amlodipine regimen on the oral cavity. there is controversy regarding the cause and effect relationship of periodontal health and drug induced gingival overgrowth. therefore, this study was conducted to investigate and to assess the relationship between the periodontal health and the onset and severity of gingival overgrowth in hyperten...