نتایج جستجو برای: hyperplastic polyp
تعداد نتایج: 11834 فیلتر نتایج به سال:
Low folate status is a risk factor for colon carcinogenesis; mechanisms proposed to account for this relationship include uracil misincorporation into DNA and global DNA hypomethylation. We investigated whether such biomarkers are related to folate status in isolated colonocytes from colonoscopy patients. In cases with adenomatous polyps (n = 40) or hyperplastic polyps (n = 16), colonocytes wer...
Background & Aims: Polyp is a protruding mass into the intestinal tract, which can be pedunculated or not. It is believed that most of colorectal cancers arise from adenomatous polyps. Materials & Methods: In this cross-sectional study pathology reports of 246 patients were evaluated. Results: In our study 64.2% of patients were male and 35.8% were female. The mean age of patients was 52.54±1...
Endocytoscopy is an emerging endoscopic imaging modality enabling real-time in vivo visualization of the superficial mucosal layer at a magnification up to 1400fold. This allows analyzing ultrastructural features of a tissue, including the arrangement and density of cells, the nucleus-tocytoplasm ratio, and the microvascular network [1]. Endocytoscopy is based on the principle of contact light ...
The purpose of this study is to identify colorectal serrated lesions in the inflammatory mucosa of inflammatory bowel disease (IBD), to characterize their molecular status based on BRAF and KRAS mutations, mismatch-repair (MMR) deficiency and microsatellite instability (MSI), and to verify that these molecular alterations are specific to the 'serrated neoplasia pathway' in IBD. Neoplastic lesio...
Optical diagnosis of polyp histology can potentially result in enormous cost savings by way of the "resect and discard" strategy for diminutive polyps and the "do not resect" strategy for diminutive hyperplastic polyps in the distal colon. Narrow Band Imaging (NBI) highlights the surface mucosal and vascular pattern on polyps and has been shown to accurately characterize adenomatous and hyperpl...
M cells are found in intestinal follicle associated epithelium. Studies into the physiological and pathological roles of human M cells have been hampered by the lack of well-substantiated, specific markers for these cells. A critical literature review suggests the following molecules may potentially serve as such markers: CK7, FcaR (CD89), S100, CD1a, CD21, CD23, sialyl Lewis A, and cathepsin E...
The majority of polyps in the colon are hyperplastic polyps, adenomas, and inflammatory polyps (Table 1). Pathologists usually receive material in the form of biopsies or endoscopic polypectomy specimens. The role of the pathologist is to establish a diagnosis, or at least to be able to put it into one of the general polyp categories, and to determine whether the lesion has been adequately exci...
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