CONTEXT Recent implantable cardioverter-defibrillator (ICD) advisories and recalls have caused management dilemmas for physicians, particularly because there are no specific guidelines or data on outcomes from current management strategies. The risk of ICD generator replacement has not been assessed in this population. OBJECTIVE To determine the complication rate associated with ICD generator...

A 46-year-old man presented to our institution with inappropriate implantable cardioverter-defibrillator (ICD) shock delivery. The ICD (single chamber, dual shock coils) was implanted for sustained monomorphic ventricular tachycardia with unstable hemodynamics and underlying systolic left ventricular dysfunction. ICD interrogation revealed recurrent episodes of ICD shock due to noise sensing an...

Statistical tomographic reconstruction algorithms generally require the efficient optimization of a functional. A recent algorithm known as iterative coordinate descent with Newton-Raphson updates (ICD/NR) has been shown to be much more computationally efficient than indirect optimization approaches based on the EM algorithm. However, while the ICD/NR algorithm has experimentally been shown to ...

Small numbers of patients are a special challenge for rare diseases research. Electronic health record (EHR) data can facilitate research if patients with rare diseases can be reliably identified. We estimate the coverage of the names of a set of 6,519 rare diseases. Using the UMLS, 697 (11%) diseases were matched to ICD-9-CM, 1,386 (21%) to ICD-10-CM and 2,848 (44%) to SNOMED CT. Using publish...

You have no doubt heard about the eight-fold increase in diagnosis codes included in the transition from ICD-9 to ICD-10, but that is not the whole story. You’ll be relieved to know that, for some encounters and services, ICD-10 offers fewer or the same number of codes. Codes related to preventive services are examples of this. This article will focus on how to select ICD-10 codes for immunizat...

BACKGROUND Racial and ethnic minorities are under-represented in clinical trials of primary prevention implantable cardioverter-defibrillators (ICDs). This analysis investigates the association between primary prevention ICDs and mortality among Medicare, racial/ethnic minority patients. METHODS AND RESULTS Data from Get With The Guidelines-Heart Failure Registry and National Cardiovascular D...