BACKGROUND Determination of relationships between transcranial Doppler (TCD)-based spectral pulsatility index (sPI) and pulse amplitude (AMP) of intracranial pressure (ICP) in 2 groups of severe traumatic brain injury (TBI) patients (a) displaying plateau waves and (b) with unstable mean arterial pressure (MAP). METHODS We retrospectively reviewed patients with severe TBI and continuous TCD m...

OBJECT The object of this study was to investigate whether a failure of cerebrovascular autoregulation contributes to the relationship between age and outcome in patients following head injury. METHODS Data obtained from continuous bedside monitoring of intracranial pressure (ICP), arterial blood pressure (ABP), and cerebral perfusion pressure (CPP = ABP - ICP) in 358 patients with head injur...

AIm: Monitoring of intracranial pressure (ICP), local cerebral blood flow (CBF) and oxygen is part of modern intensive critical care medicine. Preclinical evaluation of newly developed catheters that should monitor several parameters simultaneously is reported poorly in the literature. The goal of our study was (1) to evaluate a new multi-parametric sensor in brain tissue and (2) to establish a...

Intracranial pressure (ICP) measurement is an extremely important part of the neurosurgical armamentarium. Not only is raised ICP the commonest cause of death in neurosurgical patients, it is extremely common in patients suffering from head injury. In this latter group, 40% of patients who are admitted in an unconscious state have raised ICP, and in 50% of those who die, raised ICP is the main ...

BACKGROUND Both intracranial pressure (ICP) and the cerebrovascular pressure reactivity represent the dysregulation of pathways directly involved in traumatic brain injury (TBI) pathogenesis and have been used to inform clinical management. However, how these parameters evolve over time following injury and whether this evolution has any prognostic importance have not been studied. METHODS AN...

The real-time monitoring of intracranial pressure (ICP) is very important for craniocerebrally critically ill patients, but it is very difficult to realize long-time monitoring for the traditional invasive method, which very easily infects patients. Many noninvasive methods have emerged, but these have not been able to monitor ICP for long periods in real time, and they are not ready for clinic...

The feasibility and accuracy of using checklists after every working shift in a bedside computer-based information system for documentation of secondary insults in the neurointensive care unit were evaluated. The ultimate goal was to get maximal attention to avoid secondary insults. Feasibility was investigated by assessing if the checklists were filled in as prescribed. Accuracy was evaluated ...

In 1841 Magendi pioneered to measure cerebrospinal fluid pressure using the ‘‘sphygmometer,’’ an instrument originally designed for assessment of blood pressure. From then on, it took 110 years before the first intracranial pressure (ICP) monitoring data has been published in 1951, first ever introducing the important key-word of ‘‘monitoring’’ in the context of the human brain [1]. From this m...

The objectives are to investigate the peculiarities of the ultrasound pulse propagation through human extra/intracranial media by mathematical simulation and to confirm the simulation results experimentally by proving the suitability of the ultrasonic time-of-flight measurement method for human intracranial media (IM) physiological non-invasive monitoring. The mathematical model of ultrasound p...

CONTEXT Although osteopathic manipulative treatment (OMT) is used to manage myriad conditions, there has been some hesitation regarding the safety of applying OMT to patients with intracranial injuries or elevated intracranial pressure (ICP). OBJECTIVE To assess the safety of two OMT techniques--pedal pump and thoracic pump--on ICP and cerebral perfusion pressure (CPP) in patients with trauma...