item Frequency Percentage With scores ≥4.50 Type of cea No 0 0 Yes 216 100 Description of intervention No 1 0.5 Partial 1 0.5 Yes 214 99 Description of comparator No 13 6.0 Partial 83 38 Yes 120 56 With scores 4.00–4.49 Target population No 18 8.3 Yes 198 92 Time horizon No 114 53 Yes 102 47 Perspective No 81 38 Partial 4 1.9 Yes 131 61 How denominator was derived No 17 7.9 Yes 199 92 cea ratio...

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We read with interest the article from Shanin et al. about the Fungal Infection Risk Evaluation (FIRE) study [1] aiming to ‘describe the incidence of IFD in UK critical care units and to develop and validate a clinical risk prediction tool to identify non-neutropenic, critically ill adult patients at risk of IFD’. The investigators should be congratulated for the way they collected a huge amoun...

For a fair coin p = 12 . Therefore, H(X) = 2. (b) We need for each question to reduce our uncertainty about X as much as possible. To do this, we should ask questions which are equally likely to receive a yes or no answer. Before we start asking questions, X = 1 is just as likely as X > 1 (since p = 12 for a fair coin); all other specific values X = 1, 2, . . . are less likely. So the first que...

Two experiments are reported in which 5s were presented two strings of letters simultaneously, with one string displayed visually above the other. In Exp. I, 5s responded "yes" if both strings were words, otherwise responding "no." In Exp. II, 5s responded "same" if the two strings were either both words or both nonwords, otherwise responding "different." "Yes" responses and "same" responses we...

lung function. Did you take this into account as well? Dr Mitilian: We did take it into account, but the main criterion was the predicted donor TLC, as previously described by your team and other teams actually. Dr G. Dellgren (Gothenburg, Sweden): I’m a little bit curious about the six bipartitioned lungs. How did it go for those 6 patients? Dr Mitilian: You mean specific follow-up? Dr Dellgre...

We demonstrate that the answer to the question posed in the title is “yes” and “no”: “no” if the set of permissible operations is restricted to {+,−,×,/,mod,<}; “yes” if we are also allowed a gcd-oracle as a permissible operation. It has been shown (see [Sto76, MST91]) that no strongly polynomial algorithm exists for the problem of finding the greatest common divisor (gcd) of two arbitrary inte...

The pathwidth of a graph is a measure of how path-like the graph is. Given a graph G and an integer k, the problem of finding whether there exist at most k vertices in G whose deletion results in a graph of pathwidth at most one is NP-complete. We initiate the study of the parameterized complexity of this problem, parameterized by k. We show that the problem has a quartic vertex-kernel: We show...

1 SOF Analysis Plan Submission Form Date: October 20, 2010 Investigator’s Name: Tina Hoang Clinical Center: UCSF Sponsor (if not a SOF investigator): Kristine Yaffe Telephone:415-221-4810 ext 3792 e-mail: [email protected] Other investigators who will be working on this analysis: Peggy Cawthon Analysis Plan Title: The relationship between alcohol consumption and cognitive outcomes in the oldest...