نتایج جستجو برای: immune mediated thrombocytopenia

تعداد نتایج: 656572  

Journal: :Blood 2002
Jeffrey T Billheimer Ira B Dicker Richard Wynn Jodi D Bradley Debra A Cromley Helen E Godonis Lisa C Grimminger Bokang He Cathy J Kieras Donna L Pedicord Susan M Spitz Beth E Thomas Nina I Zolotarjova Mary A Gorko Gregory F Hollis Robert N Daly Andrew M Stern Dietmar Seiffert

Glycoprotein (GP) IIb/IIIa antagonists are effective therapeutic agents, but elicit thrombocytopenia with a frequency that approaches 2%. Here, we provide evidence that thrombocytopenia in humans treated with the GP IIb/IIIa antagonist roxifiban is immune mediated. Two patients underwent conversion to a highly positive drug-dependent antibody (DDAB) status temporally associated with thrombocyto...

Journal: :Journal of the South African Veterinary Association 2014
Chantal T Rosa Paolo Pazzi Salome Nagel Vanessa McClure Jevan Christie Milana Troskie Eran Dvir

Theileriosis is a tick-borne disease caused by a piroplasma of the genus Theileria that can causeanaemia and thrombocytopenia. Its clinical importance for dogs' remains poorly understood,as only some develop clinical signs. In this study, physical and laboratory findings, treatment and outcomes of six client-owned diseased dogs presented at the Onderstepoort Veterinary Academic Hospital are des...

Journal: :Blood 1987
W S Court J M Bozeman S J Soong M N Saleh D R Shaw A F LoBuglio

We quantitated the amount of platelet surface-bound IgG using an 125I monoclonal anti-IgG assay in 149 patients with thrombocytopenia and 260 normal donors. The normal subjects had 122 +/- 5 molecules of IgG/platelet (mean +/- SE). Fifty-five patients with nonimmune thrombocytopenia had 338 +/- 37 molecules of IgG/platelet, whereas 67 patients with immune thrombocytopenia studied at the time of...

Journal: :Hematology/Oncology Clinics of North America 2009

Journal: :American Journal of Hematology 2019

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