نتایج جستجو برای: immunologic reaction
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BACKGROUND In 2009, there was an influenza pandemic in South Korea. The aim of this study was to evaluate the epidemiological, clinical and laboratory characteristics of this infection in children and adults. METHODS We evaluated the epidemiologic characteristics of patients infected with the 2009 H1N1 influenza A virus (4,463 patients, age range from 2 mo to 86 y), and the clinical and labor...
PURPOSE Active immunotherapy is emerging as a potential therapeutic approach for prostate cancer. We conducted the first phase I trial of an Ii-Key/HER-2/neu(776-790) hybrid peptide vaccine (AE37) with recombinant granulocyte macrophage colony-stimulating factor as adjuvant in patients with HER-2/neu(+) prostate cancer. The primary end points of the study were to evaluate toxicity and monitor p...
We report the outcome of allogeneic bone marrow transplantation (BMT) as treatment for severe combined immunodeficiency disease (SCID) in 31 patients grafted from 1968 until 1992. The patients received a graft from an HLA-identical related (n = 10), an HLA-haplo-identical related (n = 19), or a closely HLA-matched unrelated (n = 2) donor that resulted in the long-term survival of 6 of 10, 9 of ...
Rather early in studies on influenza immunization in animals as well as in man, it was realized that immunizing effect, as reflected in antibody response induced by the vaccines employed, was limited and of relatively short duration. For these reasons (1) a variety of methods were explored for enhancing and prolonging the protective effect induced by vaccination (2-7). None, however, provided s...
Bone marrow transplantation in human X-linked severe Normal percentages of T cells and T-cell mitogenic recombined immunodeficiency (XSCID) without pretransplant sponses were attained by 3 months posttransplant. CD3 T conditioning results in engraftment of donor T cells and recells after transplantation expressed the CD45RA isoform constitution of T-cell function but engraftment of few, if any,...
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