نتایج جستجو برای: immunostimulatory activity
تعداد نتایج: 1135910 فیلتر نتایج به سال:
The aim of this research was to confirm the possible synergic effects sasam-Kyeongokgo (SKOG) on anti-tumor activity gefitinib using athymic nude mice bearing human non-small-cell lung squamous cell carcinoma (NSCLC) NCI-H520 line after continuous oral combination treatment provided daily for 35 days within a timeframe 5 min, as developing process novel preventive and therapeutic regimes variou...
The immunomodulatory and antimicrobial effects of methanol extract air-dried, powdered leaves Uvaria chamae (MEUL) was evaluated in this study using standard methods. Graded doses (50 mg/kg body weight, 100 200 weight 400 weight) the were administered to winster rats. control group given dimethyl sulphoxide (DMSO). Immunomodulatory effect assessed by delayed type hypersensitivity (DTH) haemaggl...
BACKGROUND Evidence for the scientific basis of purported therapeutic effects and adverse effects of herbal supplements continues to grow. Many herbal supplements are touted for their immunostimulatory properties, and both in vitro and in vivo experiments have supported this claim. Although this explains their beneficial effects in preventing or curtailing disease, to our knowledge, no immunost...
Background. Searching for drugs or herbal formulations to improve the immunity of HIV/AIDS positive people is an important issue for researchers in this field. Triphala, a Thai herbal formulation, is reported to have immunomodulatory effects in mice. However, it has not yet been investigated for immunostimulatory and side effects in healthy human volunteers. Objective. To evaluate the immunosti...
To develop an immunotherapeutic vaccine for treatment of allergic rhinitis, we developed a controlled release formulation of Cryj1, a major Japanese cedar pollen allergen, with immunostimulatory potency. Two sets of hexapod-like structured DNA (hexapodna) were prepared using six oligodeoxynucleotides (ODNs) each, including ODNs with an unmethylated cytosine-phosphate-guanine (CpG) sequence (CpG...
We developed a potential immunostimulatory double-stranded DNA (dsDNA) delivery system by the binding of dsDNA to amino-modified mesoporous silica nanoparticles (MSNs) to form MSN-NH2/dsDNA complexes. Serum stability, in vitro cytotoxicity, cell uptake, and type I interferon-α (IFN-α) induction of MSN-NH2/dsDNA complexes were evaluated. The results showed that MSN-NH2 nanoparticles had no cytot...
A high activatory/inhibitory FcγR binding ratio is critical for the activity of mAb such as rituximab and alemtuzumab that attack cancer cells directly and eliminate them by recruiting immune effectors. Optimal FcγR binding profiles of other anti-cancer mAb, such as immunostimulatory mAb that stimulate or block immune receptors, are less clear. In this study, we analyzed the importance of isoty...
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