Impulsive and aggressive behaviors are both modulated by serotonergic signaling, specifically through the serotonin 1B receptor (5-HT1BR). 5-HT1BR knockout mice show increased aggression and impulsivity, and 5-HT1BR polymorphisms are associated with aggression and drug addiction in humans. To dissect the mechanisms by which the 5-HT1BR affects these phenotypes, we developed a mouse model to spa...

Police represents an institution that regulates the social welfare where the officers assimilate the behavioral codes to perform their functions. One of the problems identified in the police officer's behaviors refers to aggressive expressions, probably linked with impulsive reactions. In this report, we show an exploratory study to elucidate the neurocognitive correlation of impulsivity in a M...

ackground: Postmortem studies in suicide victims demonstrate an increase in the number of post-synaptic 5-HT2A receptor binding sites in entral lateral and orbital frontal cortex. Diminished metabolic responses to serotonergic activation are noted in these areas in impulsive subjects ith borderline personality disorder (BPD), a group at high risk for suicidal behaviors. We examined 5HT2A recept...

The development of early intervention strategies for children with symptoms of Attention Deficit Hyperactivity Disorder (ADHD) is important because it provides an opportunity to prevent severe problems in the future. The main purpose of this investigation was to determine the efficacy of a group training for the control of attention, working memory and impulsive behaviors, involving 5-year-old ...

Children with attention deficit hyperactivity disorder (ADHD) are impulsive, inattentive and hyperactive, while children with sensory modulation disorder (SMD), one subtype of Sensory Processing Disorder, have difficulty responding adaptively to daily sensory experiences. ADHD and SMD are often difficult to distinguish. To differentiate these disorders in children, clinical ADHD, SMD, and dual ...

Serotonin (5-hydroxytryptamine, 5-HT) is a neuromodulator that is involved in a number of mood disorders such as depression, anxiety, and impulsive violence. In an attempt to dissect the contribution of individual 5-HT receptor subtypes to behavior, the authors have generated, by homologous recombination, mutant mice lacking the 5HT1B receptor. These mice did not exhibit any obvious development...

Decreased serum cholesterol has been associated with impulsive aggressive behaviors. This study was designed to explore the relationship between serum cholesterol levels and measures of impulsive aggression in personality disordered patients. Forty-two personality disordered patients (14 borderline personality disorder, 28 other personality disorders) were included. Fasting serum cholesterol wa...

This study examined risk and protective factors for nonsuicidal self-in jury (NSSI) among a large sample of Chinese community adolescents at two waves over a one-year fo llow-up period. We predicted the in itiation and stop of NSSI by changes in various NSSI correlates in 4,782 school adolescents. Participants completed questionnaires assessing NSSI, emotional vulnerability, family invalidation...

The dynamic behaviors of a predator-prey pest model with disease in prey and involving an impulsive control strategy to release infected prey at fixed times are investigated for the purpose of integrated pest management. Mathematical theoretical works have been pursuing the investigation of the local asymptotical stability and global attractivity for the semitrivial periodic solution and popula...