Background: Foot ulceration (DFU) is a serious complication of diabetes and new techniques that can predict wound healing may prove very helpful. We tested the ability of Medical Hyperspectral Technology (HT), a novel diagnostic scanning technique which can quantify tissue oxyand deoxyhemoglobin, to predict DFU healing. Methods: Ten T1DM patients with 21 foot ulcer sites, 13 T1DM without ulcers...

BACKGROUND Australia is ranked ninth of 39 countries in the Western Pacific region most affected by diabetes. Patients with diabetes are at high risk of developing foot ulcerations that can develop into non-healing wounds. Recent studies suggest that the lifetime risk of developing a diabetic foot ulcer is as high as 25%. Few studies have reported the prevalence of, risk factors and socioeconom...

In the year 2005, most of the estimated 150 million people worldwide afflicted by diabetes mellitus lived in developing countries.1 Diabetic foot ulcers will complicate the disease in more than 15% of these people during their lifetimes.2,3 In prospective cohort studies conducted among those with diabetes, history of a foot ulcer increased the risk of subsequent amputation by twoto over three-f...

This study combines non-invasive hyperspectral imaging with an experimentally validated skin optical model and inverse algorithm to monitor diabetic feet of two representative patients. It aims to observe temporal changes in local epidermal thickness and oxyhemoglobin concentration and to gain insight into the progression of foot ulcer formation and healing. Foot ulceration is a debilitating co...

BACKGROUND Kiwifruit (Actindia Deliciosa) is demonstrated to have antibacterial and pro-angiogenic effects. It also contains proteolytic enzymes (actinidin) and ascorbic acid. In this study, the effects of Kiwifruit on neuropathic diabetic foot ulcer healing in clinical settings were evaluated. MATERIALS AND METHODS In this randomized clinical trial of 37 patients (17 in experimental and 20 i...

OBJECTIVE Tissue oxygen supply is crucial for wound healing. Especially in diabetic foot lesions, the chances for healing are mainly dependent on the presence or absence of ischemia. This study investigates the impact of the tissue O2 analysis system "O2C" for noninvasive quantification of tissue oxygenation in diabetic foot ulcer patients. RESEARCH DESIGN AND METHODS O2C assessed relative bl...

Abstract There are several factors that affect the efficiency of phagocytic activity in diabetic patients. In this study, a significant difference phagocytosis showed patients and controls (non-diabetic). The means were 43.05%, 52.70% 71.35% for foot ulcer, diabetes mellitus respectively. Age groups, mean blood glucose levels controlling fasting effects on (P-value = 0.022, 0.013 0.045) was rev...

OBJECTIVE The aim was to evaluate over 18 months whether depression was associated with mortality in people with their first foot ulcer. RESEARCH DESIGN AND METHODS A prospective cohort design was used. Adults with their first diabetic foot ulcer were recruited from foot clinics in southeast London, U.K. At baseline, the Schedules for Clinical Assessment in Neuropsychiatry 2.1 was used to def...

Some diabetic patients develop a diabetic peripheral neuropathy characterised by loss of sensation in the feet. Such patients have a high risk of injuries which often go unnoticed. Diabetic patients particularly those with neuropathy have abnormal pressure points under the feet. In these area, the skin gets thickened (called callus) which then becomes an ulcer. Chronic infection in the ulcer ul...