The purpose of the present study was to investigate the context of new aspects of cellular adaptation in physical activity with a focus on delayed pain approach, the nature and types of pain, several preventive and non-pharmacological approaches to delayed onset muscle soreness (DOMS) and to achieve a desirable conclusion and provide more relevant information from previous research. In this stu...

background and objectives:wild sage(salvia macrosiphon boiss.) known as “marvak” in persian is one of the polymorphic and abundant plants of lamiaceae. the plants whole seeds usually soaked or boiled in hot water are widely used for inflammatory ailments in folk medicine. documents have shown that there is scant information on the chemical constituents of this plant seeds. the current study was...

Pro-inflammatory enzymes play a key role in inflammatory processes and are potential targets of anti-inflammatory drugs. In this study, the objective was to evaluate antiradical activity extracts their ability inhibit phospholipase A 15-lipoxygenase activity. The hydroethanolic extract revealed strongest reducing power with an IC 7.29 ± 0.61 µg/mL. three most active on PLA were (IC 21.43 0.66 ?...

isolation of pigmented t.violaceum from a patient with endothrix infection associated with the inflammatory and kerion symptoms and also isolation of the non- pigmented strain from another patient with non-inflammatory symptoms, led us to investigate the enzymic activities in both strains. most of the studies on dermatophyte compoxition have shown the relationship between proteolytic enzymes an...

non-steroidal anti-inflammatory drugs (nsaids) are the competitive inhibitors of cyclooxygenase (cox), the enzyme which mediates the bioconversion of arachidonic acid to inflammatory prostaglandins (pgs). their use is associated with the side effects such as gastrointestinal and renal toxicity. the therapeutic anti-inflammatory action of nsaids is produced by the inhibition of cox-2, while the ...

background: rheumatoid arthritis is a type of inflammatory pain and is an autoimmune and chronic inflammatory disease which can lead to hyperalgesia, edema and decreased motor activity in affected area. mesenchymal stem cells conditioned medium (msc-cm) has anti-inflammatory mediators which can regulate the immune responses, alleviate inflammatory symptoms and has a paracrine effects too. the a...

Objective(s) Aristolochia indica has been widely used in the traditional medicine for the treatment of a variety of diseases. In the present study different extracts of roots of A. indica were evaluated for their anti‌inflammatory, antipruritic and mast cell stabilizing activity. Materials and Methods Anti-inflammatory activity was performed by compound 48/80 induced rat paw edema model and ...

non-steroidal anti-inflammatory drugs (nsaids) are the most common pharmacological group that has three primary therapeutic effects including anti-inflammatory, anti-pyrexia, and analgesia. in this study, seven of nsaids were tested against two species of skin pathogenic fungi (dermatophytes). percentage inhibition was determined for effective agents. diclofenac, aspirin and naproxen showed muc...

Non-steroidal anti-inflammatory drugs (NSAIDs) are the competitive inhibitors of cyclooxygenase (COX), the enzyme which mediates the bioconversion of arachidonic acid to inflammatory prostaglandins (PGs). Their use is associated with the side effects such as gastrointestinal and renal toxicity. The therapeutic anti-inflammatory action of NSAIDs is produced by the inhibition of COX-2, while the ...

Non-steroidal anti-inflammatory drugs (NSAIDs) are the competitive inhibitors of cyclooxygenase (COX), the enzyme which mediates the bioconversion of arachidonic acid to inflammatory prostaglandins (PGs). Their use is associated with the side effects such as gastrointestinal and renal toxicity. The therapeutic anti-inflammatory action of NSAIDs is produced by the inhibition of COX-2, while the ...