Abstract The safe and targeted delivery of pharmaceutical formulations has relied extensively on synthetic chemistry other physicochemical approaches. research paradigm is now especially changing towards green (or environmentally friendly) approaches, several biopolymer‐based nanocarriers are marked as emerging nanomedicine tools. These have been developed to overcome problems with conventional...

An organism’s survival depends on its ability to adapt stress. Mitochondria are the cellular integrators of environmental stressors that ultimately translate their responses at organismal level, and thus central process whereby organisms respective environments. produce molecular energy via oxidative phosphorylation then allows cells biosynthetically respond changes in environment. Reactive oxy...

Abstract Background In spite of prolonged disease remission IBD patients, induced by the new biological molecules, a significant number them suffer from persistent debilitating symptoms with major impact on quality life. Frequently, these are due to post-inflammatory motility changes and misinterpreted as functional disorders. Our aim is identify characterize anorectal dysfunction in patients. ...

Endocannabinoid (ECB) system plays a vital role in responses to stress. Moreover, ECB and its receptors cause anti-inflammatory, anti-oxidative and neuroprotective effects by modulating neuronal, glial and endothelial cell functions. A number of studies have demonstrated ECB system notably defects in neurotraumatic and neurodegenerative diseases like epilepsy, TBI, Alzheimer’s disease and...