conclusions taken together, these data reveal that cellular protease of chicken liver cells allows the replication of high yields of h9n2 virus in the absence of trypsin and also cell death in the infected cells is due to necrosis. results the degree of viability was significantly reduced in infected hepatoma cells. observations of caspase activation and cell dna laddering in infected cells wer...

in this study, we assessed the adverse reactions to influenza vaccination in hiv- infected individuals. from november 2006 to january 2007, a total of 203 hiv-infected persons were recruited. demographic data were collected. subjects were evaluated 48 h and 15 days after vaccination for symptoms and significant health events as possible side effects. participants were instructed to measure thei...

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objective: the use of bacterial plasmids carrying specific genes of pathogens as genetic vaccines is a relatively new technique for induction of cellular immune responses against microbial pathogens. mechanisms of production of specific immune responses against these vaccines are not still completely understood. therefore, it is necessary to examine various routes of inoculation to find the bes...

background influenza type a (h1n1) causes an epidemic disease, resulting in thousands of deaths throughout the world. objectives our aim was comparing the efficacy of two different methods in isolating the influenza (h1n1) virus including cell culture and real-time pcr in tabriz and suburbs. patients and methods of throat swab samples, 220 were collected in viral transport medium (vtm) from pat...

background and aims: influenza (flu) is a respiratory infection in mammals and birds. it is caused by an rna virus in the family orthomyxoviridae. the virus is divided into three main types. influenza virus type a is found in a wide variety of bird and mammal species and can undergo major shifts in immunological properties. hemagglutinin (ha) is an important influenza virus surface antigen that...

there are many effective chemothereutic agents used in influenza disease which some of them inhibit virus replication by interfering with fluv (influenza virus) viral binding or its penetration into cell membrane. a series of polyoxometalates compounds such as pom-523 and pm-504 have been synthesized and have showed inhibitory effects on viruses. in this study we examined anti influenza activit...

Influenza affects many lives worldwide each year during the months of October through February. The 2020-2021 influenza season saw a sharp decline in cases reported United States and other countries like Great Britain comparison to previous seasons. most likely explanations for this are safety measures taken COVID-19 pandemic, such as physical distancing, face mask use, better hand hygiene mass...

Influenza B is responsible for a significant proportion of the global morbidity, mortality and economic loss caused by influenza-related disease. Two antigenically distinct lineages co-circulate worldwide, often resulting in mismatches vaccine coverage when predictions fail. There are currently operational issues with gold standard serological assays influenza B, such as lack sensitivity requir...