Modelling the software architectures of large systems is a challenging task. A wide variety of abstractions are required by developers to assist them inions are required by developers to assist them in describing and analysing such architectures, including information about the components and relationships that comprise a system, the static and dynamic structure of the system, and the behaviour...

Small area estimation techniques are employed when sample data are insufficient for acceptably precise direct estimation in domains of interest. These techniques typically rely on regression models that use both covariates and random effects to explain variation between domains. However, such models also depend on strong distributional assumptions, require a formal specification of the random p...

We propose a method that would allow for a rigorous statistical analysis of neural responses to natural stimuli, which are non–Gaussian and exhibit strong correlations. We have in mind a model in which neurons are selective for a small number of stimulus dimensions out of the high dimensional stimulus space, but within this subspace the responses can be arbitrarily nonlinear. Existing analysis ...

OBJECTIVE To analyze the Educational Project of the undergraduate medical course to verify what is taught regarding Patient Safety and to enable reflections on the educational practice. METHODS A descriptive study, using document research as strategy. The document of investigation was the Educational Project of the medical course, in 2006, at the Escola Paulista de Medicina of the Universidad...

Objective(s)Marfan syndrome (MFS) is a severe connective tissue disorder withan autosomal dominant inheritance pattern. Early diagnosis is critical in MFS. Because of the large size of fibrillin-1 gene (FBN1), the uniqueness of mutations, and the absence of genotype-to-phenotype correlations linkage analysis can be very helpful for early diagnosis of MFS. In this study, eight polymorphic marker...

BACKGROUND To control diabetes mellitus (DM) it is necessary to make overall changes in the life style of the patients. The aim of this study was to determine the effects of predisposing, reinforcing and enabling factors on self-care behaviors of the patients with DM in the Minoodasht city, Iran in 2012. METHODS In this quasi-experimental study, 78 people with DM were selected by convenience ...