background: radon and its daughter product are a major source of natural radiation exposure, the measurement of radon concentration in dwellings is assuming ever increasing importance. it is known from recent surveys in many countries that radon and its progeny contributes significantly to total inhalation dose and is well established that radon when inhaled in large quantity causes lung disord...

the viewpoint of not only animal welfare but also the reliability of pharmacological studies. The type of anesthetics used may vary depending on the type of experiment required or the study design. Some anesthetics have cardioor renoprotective effects, which may be relevant in designing ischemiareperfusion protocols. Several studies have examined the influence of commonly used anesthetics on th...

As pulmonary drug deposition is a function of aerosol particle size distribution, it critical that the dynamics formation and maturation in pMDI sprays interim between generation inhalation are fully understood. This paper presents an approach to measure evaporative condensational fluxes volatile components water from solution droplets following using novel technique referred as Single Particle...

PURPOSE Inhalation injury is one of the most severe morbidity and mortality factors in burn patients. The purpose of this study is to analyze the impact of inhalation injury to the prognosis of burn patients and to investigate the relationship between the inhalation injury assessment and the prognosis of patients. METHODS Bronchoscopy was performed in 170 patients who had the suspicion of inh...

BACKGROUND Inhalation of endotoxin (LPS) induces a predominantly neutrophilic airway inflammation and has been used as model to test the anti-inflammatory activity of novel drugs. In the past, a dose exceeding 15-50 μg was generally needed to induce a sufficient inflammatory response. For human studies, regulatory authorities in some countries now request the use of GMP-grade LPS, which is of l...

Background: Radon and its daughter product are a major source of natural radiation exposure, the measurement of radon concentration in dwellings is assuming ever increasing importance. It is known from recent surveys in many countries that radon and its progeny contributes significantly to total inhalation dose and is well established that radon when inhaled in large quantity causes lu...

In response to the epidemic and pandemic threats caused by emerging respiratory viral infections, a safe efficient broad-spectrum antiviral therapy at early onset of infection can significantly improve patients’ outcome. Inhaled dry powder is easy administer delivers agent directly primary site infection, thereby minimizing systemic side effects. Here, spray freeze drying (SFD) technique employ...

The use of biomass indoor Honai (traditional house) in Wamena have been conducted for several decades and become a traditional habit of Honai occupants. Since air temperature at night in Wamena Regency is cold the inhabitans burn the Kasuari woods to warm their body. As a result, they continuously inhale the Sulfur Dioxide (SO2) and Nitrogen Dioxide (NO2) and some contaminated air in Honai room...