نتایج جستجو برای: inherited inferiority
تعداد نتایج: 34895 فیلتر نتایج به سال:
OBJECTIVE To show non-inferiority of trimethoprim-sulfamethoxazole compared with vancomycin for the treatment of severe infections due to meticillin resistant Staphylococcus aureus (MRSA). DESIGN Parallel, open label, randomised controlled trial. SETTING Four acute care hospitals in Israel. PARTICIPANTS Adults with severe infections caused by MRSA susceptible to trimethoprim-sulfamethoxaz...
The trivalent inactivated influenza vaccine Fluarix™ is licensed in the US for adults and children from 3 years old. This randomized observer-blind study (NCT00764790) evaluated Fluarix™ at two doses; 0.25 ml (Flu-25) and 0.5 ml (Flu-50) in children aged 6-35 months. The primary objective was to demonstrate immunogenic non-inferiority vs. a control vaccine (Fluzone®; 0.25 ml). Children received...
The ICH-E10 guideline on the choice of control group in clinical trials was a long awaited document. The concept paper gave reason to hope that it would give clear and harmonised guidance to an area, which has been very much disputed, including the burning issue of the role of placebo control. In the main, the final guideline was disappointing in spite of the long preparation time. In many resp...
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