OBJECTIVES The COLEP trial in Bangladesh showed a 57% reduction in leprosy incidence among contacts of newly diagnosed patients in the first 2 years after chemoprophylaxis with single dose rifampicin (SDR). We assessed the impact of this intervention after 6 years and identified characteristics of the leprosy index patients predicting the effectiveness of this intervention. DESIGN The cohort ...

Objective To determine whether general practice surveillance for childhood obesity, followed by obesity management across primary and tertiary care settings using a shared care model, improves body mass index and related outcomes in obese children aged 3-10 years. Design Randomised controlled trial. Setting 22 family practices (35 participating general practitioners) and a tertiary weight manag...

Objective: The aim of the present study was to examine the effectiveness of Acceptance and Commitment Therapy (ACT) combined with aerobic exercise (AE) on anxiety symptoms, insulin resistance (IR) and lipid profile in women with T2DMmellitus (T2DM). Materials and Methods: In the present study, 60 T2DM women with a mean age of 33.5 (± 3.52) years were selected from the patients who were referre...

OBJECTIVES The Teeth Tales trial aimed to establish a model for child oral health promotion for culturally diverse communities in Australia. DESIGN An exploratory trial implementing a community-based child oral health promotion intervention for Australian families from migrant backgrounds. Mixed method, longitudinal evaluation. SETTING The intervention was based in Moreland, a culturally di...

Since the use of tumor necrosis factor (TNF) inhibitor therapy is becoming wider, the effects of concurrent intervention with exercises and stabilized TNF inhibitors therapy in patients with ankylosing spondylitis (AS) are different. The study aimed to objectively evaluate whether concurrent intervention with exercises and stabilized TNF inhibitors can reduce the disease activity in patients wi...

OBJECTIVE To prospectively examine the effects of a randomized school-based intervention on nutrition and physical activity knowledge and preferences, anthropometric measures, and fitness in low socioeconomic kindergarten children. STUDY DESIGN A total of 376 children completed a school-year combined dietary-behavioral-physical activity intervention and were compared with 349 control subjects...

OBJECTIVE To evaluate the impact of a worksite diabetes prevention intervention on secondary outcomes regarding the change in diet quality and components of the Health Action Process Approach (HAPA) theoretical framework. DESIGN Pretest-posttest control group design with 3-month follow-up. SETTING University worksite. PARTICIPANTS Employees aged 18-65 years with prediabetes (n = 68). IN...

BACKGROUND High blood pressure (BP) is a leading contributor to cardiovascular mortality globally. There is scarcity of information on effective health systems interventions to lower BP and reduce cardiovascular risk in Southeast Asian countries. We conducted a pilot exploratory trial on 100 adults aged 40 years or older with uncontrolled hypertension to optimize the design for a structured mul...

BACKGROUND The aim of this study was to explore the potential benefits of the Dejian mind-body intervention (DMBI) for psychological and physical health in older Chinese adults. METHODS After confirmation of eligibility, the subjects were invited to receive DMBI once a week for 12 weeks. The intervention involved components of learning self-awareness and self-control, practicing mind-body exe...