Lumbar discectomy for relief of sciatica in patients with intervertebral disc herniation (IDH) is one of the most wellresearched and common indications for spine surgery. There is good evidence that lumbar discectomy for carefully selected patients with sciatica as the result of lumbar disc herniation provides faster relief of symptoms than nonoperative treatment [1,2]; however, randomized tria...

Transforaminal lumbar interbody fusion (TLIF) is a relatively new technique of lumbar arthrodesis via posterior transforaminal approach to the disc, indicated mainly in cases of degenerative disc disease, low grade spondylolisthesis and reoperation for disc herniation, specially when there is indication for interbody fusion and posterior decompression. The main advantage of TLIF is that it allo...

BACKGROUND To investigate the effect of oxygen-ozone (O2-O3) injection on thoracolumbar intervertebral disc herniation (IVDH) in dogs. MATERIALS AND METHODS Ten herniated discs of five dogs were treated with percutaneous injection of an O2-O3 gas mixture with O3 concentration of 32 microg/microl intradiscally (1.5-2 microl) under fluoroscopy guidance. RESULTS Five weeks after treatment, the...

Even though intervertebral disc degeneration can be found in the natural course of alkaptonuria, detection of the disease by black disc color change in a patient without any other presentation of alkaptonuria is an exceptionally rare condition. We have reported a very rare case of alkaptonuria presented with low back pain and steppage gait in a 51-year-old male with a complaint of chronic low-b...

INTRODUCTION Regeneration of nucleus pulposus (NP) tissues in the early stages of degeneration can theoretically retard or even reverse the degenerative process and possibly restore a healthy intervertebral disc (IVD). The approval of autologous disc cell transplantation (ADCT) in Germany demonstrated the potential for cell-based therapies of IVD degeneration. The most clinically applicable sou...

A 16 year old girl did a handstand for fun, returned to her feet, experienced a sudden pain in her back, and became progressively paraplegic within 30 hours. MRI showed lumbar cord swelling, multiple Schmorl's nodes, a collapsed T11-T12 disc space, and intraspongious disc prolapse into the T12 vertebral body. These findings, related to the initial manoeuvre, suggested that an acute vertical dis...

BACKGROUND Tissue compression and noxious stimuli are known to elicit pain from neural tissues in the spine. Compression of nerve roots due to decreases in the intervertebral foramina may be caused by posture, sustained loading and disc height loss, herniation, or altered mechanics. It has been established that non-neutral postures combined with repeated loading can cause disc herniations, howe...