objective(s): the aim of the present study is to determine the effect of chloramphenicol (cap) on rat liver and small intestine. effect of phenobarbital (pb) on cap toxicity was also investigated.   materials and methods:   rats were received cap at doses of 0, 200, 400 and 600 mg/kg. another group was pretreated with 80 mg/kg pb 30 min prior to administration of various doses of cap. the exper...

background isolated small gut mesentery injury after blunt abdominal trauma from the steering wheel in road traffic accidents is rare. these are always challenging to diagnose and pose a diagnostic dilemma. objectives to study the pattern of small gut mesenteric injury by steering wheel blunt abdominal trauma in road traffic accidents in patients who had laparotomy. patients and methods a 10-ye...

the aim of this study was to investigate the effects of dietary garlic on the growth performance, intestinal mucosa morphology, and pulmonary hypertensive response in broiler chickens with pulmonary hypertension induced by 3, 5, 3′-l triiodothyronine. chicks were reared for 42 days and treated with triiodothyronine (1.5 mg/kg diet) and 0 (control), 0.2, 0.6 or 1% garlic powder. intestinal segme...

The extracellular matrix (ECM) has been successfully used as a scaffold for constructive remodeling of multiple tissues in both preclinical studies and in human clinical applications. The basement membrane is a specialized form of the ECM that supports and facilitates the growth of epithelial cell populations. The morphology and the molecular composition of the ECM, including the basement membr...

Weaning stress caused marked changes in intestinal structure and function. Transforming growth factor-β1 (TGF-β1) and canonical Smads signaling pathway are suspected to play an important regulatory role in post-weaning adaptation of the small intestine. In the present study, the intestinal morphology and permeability, developmental expressions of tight junction proteins and TGF-β1 in the intest...

This study evaluated the effects of elevated incubation temperature on posthatch nutrient transporter gene expression, integrity of the intestinal epithelium, organ development, and performance in Ross 308 broiler chickens. Ross × Ross 308 fertile eggs (n = 900) were incubated at different eggshell temperatures during development. From embryonic day (ED) 1 to ED12, all eggs were incubated at 37...

The effects of replacing groundnut cake(GNC) with cottonseed cake (CSC) at 0, 50 and 100% levels in starter finisher diets on broiler performance, carcass characteristics gut morphology were evaluated a 56 - day feeding trial. Average daily feed intake, average weight gain, feed/gain ratio significantly (P< 0.05) affected by dietary treatments the phases. Eviscerated (E. W) dressing percenta...

BACKGROUND The application of hydroxyethyl starch (HES) for volume resuscitation is controversially discussed and clinical studies have suggested adverse effects of HES substitution, leading to increased patient mortality. Although, the intestine is of high clinical relevance and plays a crucial role in sepsis and inflammation, information about the effects of HES on intestinal function and bar...

AIMS To investigate E-cadherin expression in normal and inflamed intestine, in the colonic adenocarcinoma cell line HT29, in normal fetal intestine, and in a fetal gut organ culture model where a T cell mediated enteropathy can be generated; to determine whether expression of E-cadherin changes in intestinal inflammation. METHODS Immunohistochemistry was used to determine E-cadherin expressio...