E604 CMAJ, June 14, 2011, 183(9) © 2011 Canadian Medical Association or its licensors A45-year-old man was brought to the emergency department by his family because of a change in personality and inappropriate behaviour that had progressed over several years. In the weeks before admission, he had become increasingly agitated, confused and lethargic. On examination, he was drowsy and displayed f...

Sildenafil is one of the most commonly used drugs for the treatment of erectile dysfunction. To date, we found five reported cases of intracerebral bleeding and two reported cases of subarachnoid hemorrhage related to sildenafil use. We report a 49-year-old hypertensive and diabetic patient who presented with acute pulmonary edema and loss of consciousness following ingestion of 100 mg of silde...

OBJECTIVE The purpose of this study was to retrospectively evaluate and compare the incidence of diffusion-weighted image (DWI) lesions between the Guglielmi detachable coil (GDC) and the Target coil for treating unruptured intracranial aneurysm. METHODS From 2010 to 2011, consecutive 222 patients with an intracranial aneurysm underwent coil embolization. Inclusion criterias were : 1) unruptu...

We describe a 53-year-old mother and a her 34-year-old son who suffered from spontaneous subarachnoid hemorrhage (SAH) and/or intracerebral hemorrhage due to a ruptured intracranial aneurysm. Diagnosis of the intracranial aneurysm was made by CT scan of the brain, and cerebral angiography. These two cases received surgical intervention and returned to their previous social activity after discha...

BACKGROUND Although Saccular intracranial aneurysm (sIA) is the most common type abnormality of all intracranial aneurysms, the biological mechanisms of sIA are not fully understood. METHODS We downloaded microarray datasets from Gene Expression Omnibus (GEO) database which includes 11 ruptured intracranial aneurysm samples and 8 unruptured intracranial aneurysm samples. Significant Analysis ...

Thunderclap headache is a sudden, high-intensity headache often associated with subarachnoid hemorrhage secondary to a ruptured intracerebral aneurysm. A variety of less common causes have now been described. This report presents the cases of 2 patients who experienced thunderclap headache after regrowth of an aneurysm, without hemorrhage of previously coiled aneurysms. Thunderclap headache aft...

AIMS The purpose of this study was to assess the clinical value of indocyanine green angiography (ICG) in intracranial aneurysm surgery by comparing the findings with postoperative angiographic results. MATERIALS AND METHODS One hundred and twenty patients with 148 intracranial aneurysms were included. ICG angiography was performed before and/or after the aneurysm clipping. A near-infrared ex...

BACKGROUND AND PURPOSE Our aim was to determine the diagnostic accuracy of multisection CT angiography combined with matched mask bone elimination (CTA-MMBE) for detection of intracranial aneurysms compared with digital subtraction angiography (DSA) and 3D rotational angiography (3DRA). MATERIALS AND METHODS Between January 2004 and February 2006, 108 patients who presented with clinically su...