BACKGROUND Hemangiomas, one of the most common childhood neoplasms, exhibit a characteristic history of rapid proliferation and slow spontaneous involution. Most of hemangiomas are often managed conversatively, requiring numerous years for spontaneous involution. However hemangiomas can threaten function in 10% to 20% of cases, less than 1% are truly life threatening. All these serious hemangio...

background cutaneous leishmaniasis (cl) is an endemic disease in iran. pentavalent antimonials including meglumine antimoniate (ma) are still the gold standard treatment. trichloroacetic acid (tca) is used in treatment of acne scar, photodamaged skin, and some other dermatologic diseases. considering the tca potential to induce collagen synthesis and its efficacy in the treatment of papular cl ...

BACKGROUND Although intralesional methotrexate (MTX) is an effective, nonsurgical treatment of keratoacanthoma (KA), there have not been many reports of on the MTX treatment for KA in Korea. OBJECTIVE The purpose of this study was to evaluate the clinical efficacy of the intralesional MTX for the treatment of KA in Korean patients. METHODS We retrospectively studied seven patients with KA w...

IMPORTANCE Low-flow orbital or periorbital venous malformation (OVM) is the most common periorbital vascular lesion that may produce an appearance defect, visual dysfunction, internal hemorrhage, and thrombosis. Intralesional injection of pingyangmycin as a minimally invasive, gentle intervention may have better outcomes in treating low-flow OVMs compared with other currently used methods. OB...

This study was conducted to identify the effectiveness of platelet-rich plasma (PRP) and efficacy of intralesional injection as a method of application to acute cutaneous wounds in dogs. Healthy adult beagles (n = 3) were used in this study. Autologous PRP was separated from anticoagulant treated whole blood in three dogs. Cutaneous wounds were created and then treated by intralesional injectio...

BACKGROUND To evaluate the safety and efficacy of intralesional pingyangmycin for treatment of orbital vascular malformations. METHODS Thirteen patients received intralesional injections of pingyangmycin at the Eye and ENT Hospital of Fudan University. CT scans of each patient were evaluated with graphic processing software to measure lesion volumes before and after treatment. RESULTS Of fi...