The use of intrapleural instillation of recombinant tissue plasminogen activator (r-tPA) in the treatment of pleural infection may increase pleural fluid drainage associated with a clinical and imaging improvement, leading to a faster resolution. The use of r-tPA is generally well tolerated. Here we report 2 cases of massive pleural hemorrhage resulting in life-threatening hypovolemia, in 2 pat...

The histopathologic findings were compared from 20 mg/kg intrapleural tetracycline hydrochloride (TCN) and three doses of intrapleural minocycline hydrochloride (5, 10, and 20 mg/kg) (MCN) in New Zealand white rabbits. Both TCN and MCN produced an early neutrophilic predominant pleural effusion that became mononuclear over 48 h. There was no difference in pleural fluid accumulation, number of a...

conclusions both methods lia and sfnb provided excellent pain relief and lower morphine consumption following tka. lia is a surgeon-controlled analgesic technique, which can be used to enhance patients’ satisfaction and reduce the pain in the very early postoperative period by surgeon independently. results group i had significantly lower morphine consumption in the first postoperative day (10 ...

Systemic antibiotics started before operation have been found to give inadequate prophylaxis against postpneumonectomy empyema in our practice. Experimental work by others has suggested that combining this treatment with topical irrigation and intrapleural antibiotics would give improved results. We have adopted this suggestion and found it to give better prophylaxis where pneumonectomy is asso...

A pilot study of topical (intrapleural) treatment with Corynebacterium parvum was carried out in 10 patients with malignant pleural effusions complicating primary or secondary neoplasms and necessitating frequent thoracocentesis for symptomatic relief. The method was aspiration of all intrapleural fluid except a small portion left for dilution, and then injection of 7 mg of a preparation of Cor...

more diseased part of the lung which is in greatest need of collapse. In the earlier years of artificial pneumothorax treatment attempts were made to sever these adhesions by thoracotomy (by the open method). This was attended with many com, plications and the procedure is not now considered justifiable. In 1910 Jacobeus introduced the present method of intrapleural pneumolysis and invented the...

Semi-invasive aspergillosis is a rare disease leading to severe complications even in fully immunocompetent patients. The therapeutic role of systemic and intrapleural antifungal agents remains not well known. We report herein the case of a 54-year-old woman who developed Aspergillus empyema invading the thoracic wall and subcutaneous tissues after completion pneumonectomy for aspergilloma. She...