It is accepted that intravenous fluid (IVF) therapy can result in hospital-acquired dysnatremias in pediatric patients, with associated morbidity and mortality. There is interest in improving IVF therapy to prevent dysnatremias, but the optimal approach is controversial. In this study, we develop Natremia Deviation and Intravenous Renderer (NaDIR), a tool that preprocesses large volumes of elec...

OBJECTIVE To describe a 71-year-old woman who developed clinical and neuroradiological features of posterior reversible leukoencephalopathy syndrome with a compromised blood-brain barrier after 5 days of intravenous linezolid therapy for an infected hip prosthesis. DESIGN Case report. SETTING Academic research. MAIN OUTCOME MEASURES Posterior reversible leukoencephalopathy syndrome was do...

BACKGROUND The use of intravenous bicarbonate in diabetic ketoacidosis (DKA) may be considered for patients with a pH less than 6.9 according to the American Diabetes Association. The impact of this therapy on resolution of acidosis in patients with DKA is unclear. OBJECTIVE To determine whether the use of intravenous bicarbonate therapy was associated with improved outcomes in patients with ...

BACKGROUND A conservative approach to fluid resuscitation improves survival in children with severe malaria; however, this strategy has not been formally evaluated in adults with the disease. METHODS Adults hospitalised with malaria at two tertiary referral hospitals in Myanmar received intravenous fluid replacement with isotonic saline, administered at a maintenance rate using a simple weigh...

OBJECTIVE To compare the safety and efficacy of isotonic versus hypotonic maintenance fluid in children. DESIGN Randomized controlled trial. SETTING Tertiary-level teaching hospital. PARTICIPANTS 60 children (age 0.5 to 12 years) who were admitted and anticipated to receive intravenous fluid for the next 48 hours. INTERVENTION Hypotonic fluid (Standard maintenance volume as 0.18% NaCl i...

The review presents the main aspects of iron deficiency anemia (IDA) in women reproductive age and highlights current diagnostic methods, therapy, prevention IDA. Moreover, paper contemporary views on molecular mechanisms metabolism homeostasis disruption involved endometriosis. role laboratory tests diagnosis latent symptomatic extreme importance was also described. In addition to IDA, occurs ...

The topic of intravenous (IV) fluids may be regarded as "reverse nephrology", because nephrologists usually treat to remove fluids rather than to infuse them. However, because nephrology is deeply rooted in fluid, electrolyte, and acid-base balance, IV fluids belong in the realm of our specialty. The field of IV fluid therapy is in motion due to the increasing use of balanced crystalloids, part...

Objectives To examine the prevalence of dehydration without diarrhoea among admitted children aged 1–59 months and to describe fluid management practices in such cases. Design A multisite observational study that used routine in-patient data collected prospectively between October 2013 December 2018. Settings Study conducted 13 county referral hospitals Kenya. Participants Children with admissi...