نتایج جستجو برای: involution map

تعداد نتایج: 199008  

2004
PAUL BALMER

We show that the odd-indexed derived Witt groups of a semilocal ring with trivial involution vanish. We show that this is wrong when the involution is not trivial and we provide examples.

Journal: :Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999
R C Humphreys L Hennighausen

The mammary gland undergoes extensive tissue remodeling and cell death at the end of lactation in a process known as involution. We present evidence that the prolactin-activated transcription factor signal transducer and activator of transcription 5a (Stat5a) has a crucial role in the regulation of cell death during mammary gland involution. In a transforming growth factor-alpha transgenic mous...

2015
Stephen R. Hennigar Young Ah Seo Supriya Sharma David I. Soybel Shannon L. Kelleher

Mammary gland involution is the most dramatic example of physiological cell death. It occurs through an initial phase of lysosomal-mediated cell death (LCD) followed by mitochondrial-mediated apoptosis. Zinc (Zn) activates both LCD and apoptosis in vitro. The Zn transporter ZnT2 imports Zn into vesicles and mitochondria and ZnT2-overexpression activates cell death in mammary epithelial cells (M...

2014
Sumanta Chatterjee Stephanie Bacopulos Wenyi Yang Yutaka Amemiya Demetri Spyropoulos Afshin Raouf Arun Seth

BACKGROUND Insulin like growth factors (IGFs) and their binding proteins (IGFBPs) are secreted peptides that play major roles in regulating the normal development and maturation of mammary gland. While Igfbp7 has been shown to decrease breast tumor growth, its role in regulating the normal mammary gland development has not been studied. To this end, we generated Igfbp7-null mice and examined th...

Journal: :The Biochemical journal 2001
B H Sohn H B Moon T Y Kim H S Kang Y S Bae K K Lee S J Kim

Although interleukin-10 (IL-10) is known to contribute to inflammation and pathogenesis in mammalian organs, little is known about its precise role in the mammary gland. We found that IL-10 levels fluctuated during the mouse mammary cycle, showing little expression at the lactation stage and the highest expression at the involution stage. To reveal the effects of IL-10 on involution, expression...

Journal: :Discrete Mathematics 2005
William Y. C. Chen James J. Y. Zhao

We show that the formalism of overpartitions gives a simple involution for the product definition of the Gaussian coefficients. In the formulation of our involution, an overline in the representation of an overpartition is endowed with a weight.

Journal: :Proceedings of the Edinburgh Mathematical Society 1979

2012
C. PEDRINI

We give many examples of surfaces of general type with pg = 0 for which Bloch’s conjecture holds, for all values of K2 6= 9. Our surfaces are equipped with an involution. Let S be a smooth complex projective surface with pg(S) = 0. Bloch’s conjecture states that the Albanese map A0(S)0 → Alb(S) is an isomorphism, where A0(S)0 is the Chow group of 0-cycles of degree 0 on S. It is known for all s...

Journal: :Journal of Algebra 2021

We introduce a generalization of the Euclidean algorithm for rings equipped with an involution, and completely enumerate all isomorphism classes orders over definite, rational quaternion algebras orthogonal involution that admit such algorithm. give two applications: first, any order admits has class number 1; second, we show how existence relates to problem constructing explicit Dirichlet doma...

Journal: :Cancer prevention research 2016
Gretchen L Gierach Deesha A Patel Ruth M Pfeiffer Jonine D Figueroa Laura Linville Daphne Papathomas Jason M Johnson Rachael E Chicoine Sally D Herschorn John A Shepherd Jeff Wang Serghei Malkov Pamela M Vacek Donald L Weaver Bo Fan Amir Pasha Mahmoudzadeh Maya Palakal Jackie Xiang Hannah Oh Hisani N Horne Brian L Sprague Stephen M Hewitt Louise A Brinton Mark E Sherman

Elevated mammographic density (MD) is an established breast cancer risk factor. Reduced involution of terminal duct lobular units (TDLU), the histologic source of most breast cancers, has been associated with higher MD and breast cancer risk. We investigated relationships of TDLU involution with area and volumetric MD, measured throughout the breast and surrounding biopsy targets (perilesional)...

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