BACKGROUND The morbidity and mortality associated with depression are considerable and continue to increase. Depression currently ranks fourth among the major causes of disability worldwide, after lower respiratory infections, prenatal conditions, and HIV/AIDS. Crocus sativus L. is used to treat depression. Many medicinal plants textbooks refer to this indication whereas there is no evidence-ba...

PURPOSE Chronic stress has been reported to induce oxidative damage of the brain. A few studies have shown that Crocus Sativus L., commonly known as saffron and its active constituent crocin may have a protective effect against oxidative stress. The present work was designed to study the protective effects of saffron extract and crocin on chronic - stress induced oxidative stress damage of the ...

OBJECTIVE To study the biochemical and molecular hepatotoxicity induced by aluminium chloride (AlCl3) and the protective role of saffron and honey against such toxicity. METHODS This study was performed in the Department of Biology, College of Science, King Khalid University, Abha, Kingdom of Saudi Arabia between July and August 2009. Two mice strains, BALB/c and C57BL/6 (20 animals from each...

Saffron is one of the most expensive species of Chinese herbs and has been subjected to various types of adulteration because of its high price and limited production. The present study introduces a loop-mediated isothermal amplification (LAMP) technique for the differentiation of saffron from its adulterants. This novel technique is sensitive, efficient and simple. Six specific LAMP primers we...

Depressive disorders are very common in clinical practice, with approximately 11.3 of all adults afflicted during any a year. Saffron is the world's most expensive spice and apart from its traditional value as a food additive, recent studies indicate several therapeutic effects for saffron. It is used for depression in Persian traditional medicine. Our objective was to compare the efficacy of h...

Saffron (Crocus sativus) is a spice with immense economic and medicinal relevance, due to its anticancer and chemopreventive properties. Although the genomic sequence of saffron is not publicly available, the RNA-seq based transcriptome of saffron from Jammu and Kashmir provides several, yet explored, insights into the metagenome of the plant from that region. In the current work, sequence data...

Saffron (Crocus sativus) merupakan tumbuhan yang dapat digunakan sebagai obat tradisional dan juga dalam produk olahan makanan. Bahan aktif saffron, seperti flavonoid, saponin, tanin, diketahui senyawa antibakteri. fermentasi yoghurt berperan prebiotik untuk zat terkandung yoghurt, yaitu bakteri asam laktat (BAL). Bakteri patogen menyebabkan beberapa penyakit, diantaranya Pseudomonas aeruginosa...

Two commercial samples of saffron were analysed for moisture and ash contents, solubility in water, action with sulphuric acid, presence of foreign dyes and colour intensity of water soluble solution.The moisture content in Laccha was 12.7% while it was 11% in Mogra. The ash was 4.7% in both the samples. The water soluble matter in Laccha was 52.7% and 45.8% in Mogra. There was no foreign dye i...

The effects of four plant growth regulators on Crocus sativus L. (saffron) yield and performance were studied in two consecutive years under field conditions. Saffron corms immersed solutions gibberellic acid (GA3), salicylic (SA), paclobutrazol (PBZ), chlormequat chloride (CCC), distilled water (hydroprime), dry as the control. Results showed that among different treatments, plants primed with...

UV-C (254 nm)- and UV-B (280-320 nm)-light were irradiated onto bright-yellow capitula of dyer's saffron and their effects on carthamine accumulation compared. UV-C light promotes reddening of florets more prominently than UV-B light, yielding higher amounts of carthamine after the radiation process. The enhancement of carthamine synthesis by UV-C light was investigated on cellulose columns loa...