Introduction: Prostate specific antigen (PSA) is one of the most sensitive markers for diagnosis of prostate cancer. Immunoradiometric kit (IRMA) is a common and sensitive method for determination of PSA in clinical laboratories. This kit has four major components: solid phase coated with monocolonal antibody, pair antibody labelled with I-125, series of standards i...

BACKGROUND A new electrochemiluminescent immunoassay (ECLIA) has been developed for the determination of cytokeratin 19 (CYFRA 21-1) in the Elecsys 2010 immunoassay system. Urinary CYFRA 21-1 might have a role in the diagnosis of bladder cancer. METHODS We performed an analytical evaluation of the CYFRA 21-1 ECLIA for serum and urine samples. The clinical value of urinary CYFRA 21-1 for the d...

Extreme events often bring unexpected situations and impacts, as the sequence of hurricanes and other natural disasters in summer and fall 2017 demonstrated. To reduce the risks associated with such events, many have focused on reducing uncertainty in prediction or reducing vulnerability. Although both are worthy goals, we suggest that the research community should also be focusing on the natur...

The prediction of rapid intensification (RI) in tropical cyclones (TCs) is a challenging problem. In this study, the RI process and factors contributing to it are compared for two TCs: an axis-symmetric case (Hurricane Irma, 2017) asymmetric Michael, 2018). Both Irma Michael became major hurricanes that made significant impacts United States. Hurricane Weather Research Forecasting (HWRF) Model ...

Irma Nykänen1,2,3* Tiina H Rissanen4 and Sirpa Hartikainen1,3 1Kuopio Research Centre of Geriatric Care, University of Eastern Finland, Kuopio, Finland 2Research Centre for Comparative Effectiveness and Patient Safety (RECEPS), University of Eastern Finland, Kuopio, Finland 3School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland 4Institute of Public Healt...

The impact of content-based access to medical images is frequently reported but existing systems are designed for only a particular modality or context of diagnosis. Contrarily, our concept of image retrieval in medical applications (IRMA) aims at a general structure for semantic content analysis that is suitable for numerous applications in case-based reasoning or evidence-based medicine. With...

ROLAND HILDEBRAND†, STEFANO MANCINI‡ and S IMONE SEVERINI§¶ †LJK Université Joseph Fourier, Tour IRMA, 51 rue des Mathématiques, 38400 St. Martin d’Hères, France ‡Dipartimento di Fisica, Università di Camerino, Via Madonna delle Carceri 9, 62032 Camerino, Italy §Department of Computer Science, University of York, Heslington, Y010 5DD York, United Kingdom ¶Current address: Institute for Quantum ...