The myocardial injury that occurs following a period of ischaemia and reperfusion is well recognised and the underlying mechanisms have been extensively investigated in healthy myocardial tissues; however, the influence of the risk factors associated with cardiovascular diseases on ischaemia/reperfusion injury remains unclear. In this article, the present knowledge on how clinical pathologies s...

See article by Du et al. ([10], pages 919 –929) in this arteries. In other species (e.g. dog, guinea pig), the issue. occurrence of collateral arteries results in non-uniform ischaemia or even only partial ischaemia [2]. Such differMany studies have implicated the sympathetic nervous ing levels of ischaemia could have different sensitivities to system as being of importance in the genesis of th...