نتایج جستجو برای: isolated anti hb

تعداد نتایج: 688375  

Journal: :Drug metabolism and disposition: the biological fate of chemicals 2013
Ryota Higuchi Tatsuki Fukami Miki Nakajima Tsuyoshi Yokoi

Prilocaine and lidocaine are classified as amide-type local anesthetics for which serious adverse effects include methemoglobinemia. Although the hydrolyzed metabolites of prilocaine (o-toluidine) and lidocaine (2,6-xylidine) have been suspected to induce methemoglobinemia, the metabolic enzymes that are involved remain uncharacterized. In the present study, we aimed to identify the human enzym...

Journal: :The Journal of Cell Biology 1995
K Nakamura R Iwamoto E Mekada

Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a member of the EGF family of growth factors, which interact with EGF receptor to exert mitogenic activity. The membrane-anchored form of HB-EGF, proHB-EGF, is biologically active, providing mitogenic stimulation to neighboring cells in a juxtacrine mode. ProHB-EGF forms a complex with diphtheria toxin receptor-associated pr...

2016
Xiao Hu Xiaohui Lin Huabing Zhao Zihao Chen Jian Yang Fan Li Changjun Liu Feng Tian

Biofilm is a significant cause for membrane fouling. Antibacterial-coated surfaces can inhibit biofilm formation by killing bacteria. In this study, polyethersulfone (PES) microfiltration membrane was photografted by four antibiotic quaternary ammonium compounds (QACs) separately, which were synthesized from dimethylaminoethyl methacrylate (DMAEMA) by quaternization with butyl bromide (BB), oct...

Journal: :Annals of hepatology 2012
Patrícia Carvalho Maria Isabel Schinoni Jacy Andrade Marco Antônio Vasconcelos Rêgo Patrícia Marques Roberto Meyer Alex Araújo Thomaz Menezes Carolina Oliveira Rodrigo Sousa Macêdo Lucas Sousa Macêdo Júlio César Leal Betânia Matos Robert Schaer Juçara M Simones Songeli M Freire Raymundo Paraná

UNLABELLED BACKGROUND AND RATIONALE FOR THE STUDY: Hepatitis B (HB) is one of the most prevalent occupational infections in health attendance environments. According to the Brazil Ministry of Health, health professionals must be vaccinated against the hepatitis B virus (HBV) and provide laboratory proof of immunization. AIMS To evaluate the seroprevalence of HBV infection and to analyze the r...

Journal: :The Journal of biological chemistry 2005
Ganga Krishnamurthy Rajagopal Vikram Sudha B Singh Nitin Patel Shruti Agarwal Gauranga Mukhopadhyay Sandip K Basu Amitabha Mukhopadhyay

Hb endocytosis in Leishmania is mediated through a 46-kDa protein located in the flagellar pocket. To understand the nature of the Hb receptor (HbR), we have purified the 46-kDa protein to homogeneity from Leishmania promastigote membrane. Purified HbR specifically binds Hb. The gene for HbR was cloned, and sequence analysis of the full-length HbR gene indicates the presence of hexokinase (HK) ...

2003
Karène Mahtouk Michel Jourdan John De Vos Catherine Hertogh Geneviève Fiol Eric Jourdan Jean-François Rossi Bernard Klein

We previously found that some myeloma cell lines express the heparin-binding epidermal growth factor-like growth factor (HB-EGF) gene. As the proteoglycan syndecan-1 is an HB-EGF coreceptor as well as a hallmark of plasma cell differentiation and a marker of myeloma cells, we studied the role of HB-EGF on myeloma cell growth. The HB-EGF gene was expressed by bone marrow mononuclear cells of 8/8...

2010
Hiromitsu Hatakeyama Haixia Cheng Pamela Wirth Ashley Counsell Samuel R. Marcrom Carey Burton Wood Paula R. Pohlmann Jill Gilbert Barbara Murphy Wendell G. Yarbrough Deric L. Wheeler Paul M. Harari Yan Guo Yu Shyr Robbert J. Slebos Christine H. Chung

BACKGROUND We hypothesized that chronic inhibition of epidermal growth factor receptor (EGFR) by cetuximab, a monoclonal anti-EGFR antibody, induces up-regulation of its ligands resulting in resistance and that microRNAs (miRs) play an important role in the ligand regulation in head and neck squamous cell carcinoma (HNSCC). METHODOLOGY/PRINCIPAL FINDINGS Genome-wide changes in gene and miR ex...

Journal: :American journal of respiratory and critical care medicine 2006
Elizabeth S Klings Diego F Wyszynski Vikki G Nolan Martin H Steinberg

RATIONALE Pulmonary complications of sickle cell anemia (Hb-SS) commonly cause morbidity, yet few large studies of pulmonary function tests (PFTs) in this population have been reported. OBJECTIVES PFTs (spirometry, lung volumes, and diffusion capacity for carbon monoxide [DLCO]) from 310 adults with Hb-SS were analyzed to determine the pattern of pulmonary dysfunction and their association wi...

اکبری, معصومه, رضایی, مهدی, طالبی‌طاهر, مهشید, عمرانی, زهرا, محمدزاده, محبوبه, عشایری, ندا , قادریان, هما , قلی‌پور, فاطمه ,

Hepatitis B virus(HBV) is a major cause of viral hepatitis, cirrhosis and liver cancer worldwide and it is estimated to cause one million death worldwide annually. This virus is the second hazardous carcinogen in the world after smoking. According to WHO report 37% of the people in the world are infected by HBV. Healthcare workers(HCWs) are one of the high risk groups in affecting a...

Journal: :The Journal of biological chemistry 2000
R E Weber A Fago A L Val A Bang M L Van Hauwaert S Dewilde F Zal L Moens

The bimodal gill(water)/gut(air)-breathing Amazonian catfish Hoplosternum littorale that frequents hypoxic habitats uses "mammalian" 2,3-diphosphoglycerate (DPG) in addition to "piscine" ATP and GTP as erythrocytic O(2) affinity modulators. Its electrophoretically distinct anodic and cathodic hemoglobins (Hb(An) and Hb(Ca)) were isolated for functional and molecular characterization. In contras...

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