We report two cases of hepatocellular carcinoma revealed by jaundice and the presence of free-floating tumoural fragments within the biliary system. Two men (one of 64 and one of 73) presented with isolated jaundice. The results from ultrasound, CT and MRI were suggestive of a cholangiocarcinoma. Surgical intervention demonstrated bile duct thrombi from the primary tumour causing obstructive ja...

Optic nerve hypoplasia with hypopituitarism and intact septum pellucidum is a variant of septo-optic dysplasia or deMorsier's syndrome.' Although neonatal jaundice has been seen with this syndrome, the association with severe prolonged cholestatic jaundice has not been emphasised. We describe three patients who presented with cholestatic jaundice and were found to have optic nerve hypoplasia an...

Jaundice is a common neonatal problem. Since bilirubin is potentially toxic to the central nervous system, early detection and appropriate management of neonatal jaundice (NNJ) is of paramount importance, especially when bilirubin even in physiological ranges may cause permanent neuronal injury. We, therefore, undertook the present study to assess the incidence, severity, causes and therapeutic...

Obstructive jaundice often occurs as a late manifestation of non-Hodgkin’s lymphoma (NHL), but has rarely been reported as a presenting manifestation, especially in children. We report a case of a 4-year-old boy with Burkitt’s lymphoma (small non-cleaved cell NHL) who presented with obstructive jaundice, resulting from encasement of the common bile duct by the tumor. The patient underwent near-...

BACKGROUND Anesthetics are variable in patients with obstructive jaundice. The minimum alveolar concentration awake of desflurane is reduced in patients with obstructive jaundice, while it has no effect on pharmacodynamics and pharmacokinetics of propofol. In this study, we investigated the influence of obstructive jaundice on the pharmacodynamics and blood concentration of rocuronium. METHOD...

BACKGROUND AND OBJECTIVE: Hyperbilirubinemia is one of the most common problems during the neonatal period. Despite the severe complications of jaundice, no reliable data is available regarding the prevalence of acute and chronic complications of jaundice and the predisposing factors in our community. Therefore, this study aimed to determine the complications of neonatal jaundice and the predis...

The etiology and epidemiology of obstructive jaundice in Continental Croatia has been studied in 174 patients. The objective of this research was also to explore the importance and efficiency of endoscopic retrograde cholangiopancreatography (ERCP) as a non-surgical method of treatment of obstructive jaundice in the population of Continental Croatia. Obstructive jaundice is the illness of elder...

Obstructive jaundice sometimes may develop in association with advanced small-cell lung cancer (SCLC); however, SCLC initially presenting with obstructive jaundice is rare. This report presents the cases of two SCLC patients with obstructive jaundice at the initial diagnosis. A 64-year-old male presented with obstructive jaundice due to a tumor at the head of the pancreas. He was diagnosed with...

Autism spectrum disorders (ASD) are a common neurodevelopmental disorder of unknown etiology. Studies suggest a link between autism and neonatal jaundice. A 1:3 matched case-control study was conducted with children enrolled in the Military Health System born between October 2002 and September 2009. Diagnostic and procedure codes were used for identifying ASD and hyperbilirubinemia. Two definit...

Our exp~erience (1), as well as that of others (2I4), in -the treatment of acute hepatitis with steroids, has shown as the most striking effect a rapid drop of serum bilirubin. This is accompanied by the clearing of clinical jaundice. Solem and Olsen (5) have studied the influence of ACTH on the icteric index in cases of hepatitis and of post-hepatic jaundice. In the former, it dropped very rap...