PURPOSE To test the hypothesis that there is no difference in trapeziometacarpal (TMC) joint arthrosis-related symptoms and disability between patients seeking treatment for symptoms of TMC arthrosis and those with incidental TMC joint arthrosis. METHODS We compared 64 patients presenting for care of TMC joint arthrosis with 64 with incidental TMC joint arthrosis. For both groups, the diagnos...

BACKGROUND To examine the association between sonographic enthesitis and the severity of radiographic features of damage in the peripheral and axial joints in psoriatic arthritis (PsA). METHODS A cross-sectional analysis was conducted in patients with PsA. The MAdrid Sonography Enthesitis Index (MASEI) scoring system was used to quantify the extent of sonographic entheseal abnormalities. Radi...

Many sensorimotor neurons in the CNS encode global parameters of limb movement and posture rather than specific muscle or joint parameters. Our investigations of spinocerebellar activity have demonstrated that these second-order spinal neurons also may encode proprioceptive information in a limb-based rather than joint-based reference frame. However, our finding that each foot position was dete...

Meta-analyses that synthesize statistical evidence across studies have become important analytical tools for genetic studies. Inspired by the success of genome-wide association studies of the genetic main effect, researchers are searching for gene × environment interactions. Confounders are routinely included in the genome-wide gene × environment interaction analysis as covariates; however, thi...

MOTIVATION Population heterogeneity through admixing of different founder populations can produce spurious associations in genome-wide association studies that are linked to the population structure rather than the phenotype. Since samples from the same population generally co-evolve, different populations may or may not share the same genetic underpinnings for the seemingly common phenotype. O...

BACKGROUND This prospective study was performed to determine which clinical and imaging tests were most helpful for diagnosing acromioclavicular joint pain. METHODS Of 1037 patients with shoulder pain, 113 who mapped pain within an area bounded by the midpart of the clavicle and the deltoid insertion were eligible for inclusion in the study. Forty-two subjects agreed to participate, and four ...

Stiffness properties of the musculo-skeletal system can be controlled by regulating muscle activation and neural feedback gain. To understand the regulation of multijoint stiffness, we examined the relationship between human arm joint stiffness and muscle activation during static force control in the horizontal plane by means of surface electromyographic (EMG) studies. Subjects were asked to pr...

let ‎x be an ‎‎n-‎‎‎‎‎‎square complex matrix with the ‎cartesian decomposition ‎‎x = a + i ‎b‎‎‎‎‎, ‎where ‎‎a ‎and ‎‎b ‎are ‎‎‎n ‎‎times n‎ ‎hermitian ‎matrices. ‎it ‎is ‎known ‎that ‎‎$vert x vert_p^2 ‎leq 2(vert a vert_p^2 + vert b vert_p^2)‎‎‎$, ‎where ‎‎$‎p ‎‎geq 2‎$‎ ‎and ‎‎$‎‎vert . vert_p$ ‎is ‎the ‎schatten ‎‎‎‎p-norm.‎ ‎‎ ‎‎in this paper‎, this inequality and some of its improvements ...

objectives: joint attention is one of the most important prerequisite of language and social development. there are two types of joint attention, initiating joint attention and responding to joint attention. this study examined the development of responding to joint attention in typically developing children in 8-30 month. methods: this study was cross-sectional. 61 children (40 female and 20 m...

CONTEXT To date, there has been no objective validation of the phenomenon of autistic regression early in life. OBJECTIVE To validate parental report of autistic regression using behavioral data coded from home videotapes of children with autism spectrum disorder (ASD) vs typical development taken at 12 and 24 months of age. DESIGN Home videotapes of 56 children's first and second birthday ...