BACKGROUND Junctional adhesion molecule 2 (Jam2) is a member of the JAM superfamily. JAMs are localized at intercellular contacts and participated in the assembly and maintenance of junctions, and control of cell permeability. Because Jam2 is highly expressed in the luminal epithelium on day 4 of pregnancy, this study was to determine whether Jam2 plays a role in uterine receptivity and blastoc...

EB is a prototypic and heterogeneous group of inherited bullous disorders characterized by detachment the epithelium following minimal mechanical trauma. The phenotypic spectrum broad, with persistent blistering, inflammation, delayed re-epithelialization, dysfunctional wound healing often infection, leading to disability and, in most severe cases, death. classified into four subtypes: simplex ...

Title of Document: ESTROGEN AND PROGESTERONE ENHANCE NEISSERIA GONORRHOEAE TRANSMIGRATION ACROSS A POLARIZED MONOLAYER VIA A MECHANISM THAT HIJACKS EGFR. Vonetta Lisa Edwards Doctor of Philosophy, 2012 Directed By: Dr. Wenxia Song, Associate Professor Cell Biology and Molecular Genetics Gonorrhea, a common sexually transmitted infection, is caused by the gramnegative bacterium Neisseria gonorrh...

The airway epithelium comprises of different cell types and acts as a physical barrier preventing pathogens, including inhaled particles microbes, from entering the lungs. Goblet cells submucosal glands produce mucus that traps which are expelled respiratory tract by ciliated cells. Basal act progenitor cells, differentiating into epithelial types, to maintain homeostasis following injury. Adhe...

The integrity of epithelial tight junctions in foetal mammalian lungs is essential to maintain the unique ionic composition of lung liquid, and to prevent leakage of serum proteins into peripheral air spaces. In the present study the development of intercellular junctions of the lining epithelium of foetal lamb lungs during gestation was examined by light and electron microscopy. Both thin sect...

background: this study was undertaken to establish the characterization of cultured oral mucosal epithelium and introducing them as an alternative source for reconstruction of ocular surface disease. methods: human oral epithelial cells were cultured on simple media (dmem/hf12) as control and co-cultured on mitomycin c-treated 3t3 feeder layer, on the amniotic membrane (am) without nitrocellulo...