Uveitis is the most common extra-articular manifestation of juvenile idiopathic arthritis, which is the most common systemic cause of uveitis in children. Known risk factors for uveitis include antinuclear antibody seropositivity, young age of arthritis onset, specific juvenile idiopathic arthritis subtype and short duration of disease. Risk markers for severe ocular disease include gender, age...

2015 Juvenile idiopathic arthritis (JIA) is a heterogeneous condition defined by arthritis in children under age 16 at onset, lasting at least 6 weeks, without any identifiable etiology. The last 2 decades have witnessed an explosion of research into therapeutics that have allowed most children with JIA to live normal lives. One joint that has lagged behind is the temporomandibular joint. Long ...

Results 18 patients with the diagnosis of juvenile idiopathic arthritis (15 with juvenile enthesitis associated arthritis, 2 with juvenile psoriatic arthritis and 1 with juvenile idiopathic polyarticular arthritis), for a mean time of 13.7 months per patient (4-26 months). 16 patients have been treated with other biologic agents before. In 13 patients Golimumab was started because of disease pr...

Doctor Olson is with the Medical College of Wisconsin and Children’s Hospital of Wisconsin in Milwaukee, Wis. She has received funding from Amgen and Children’s Hospital Foundation. ABSTRACT Juvenile idiopathic arthritis (JIA) is the most common chronic arthropathy of childhood. Previous terminology identified this entity as juvenile rheumatoid arthritis. The 7 subsets of JIA identified under t...

Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease of childhood, with JIA-associated uveitis its most common extra-articular manifestation. JIA-associated uveitis is a potentially sight-threatening condition and thus carries a considerable risk of morbidity. The aetiology of the condition is autoimmune in nature with the predominant involvement of CD4(+) T cells. However, ...

183 Received August 5, 2015; revised and accepted September 17, 2015. Published online October 17, 2015; doi: 10.1620/tjem.237.183. Correspondence: Yingjie Zhong, Department of Pediatrics, China-Japan Union Hospital of Jilin University, No. 126, Xiantai Street, Erdao District, Changchun 130031, China. e-mail: [email protected] Blueberry Improves the Therapeutic Effect of Etanercept on Patient...

Systemic JIA represents 20% of all JIA cases. It is characterized by the onset of high-grade fever associated with multiple extra-articular manifestations. [2] These include maculopapular rash, generalized lymphadenopathy, hepatomegaly, splenomegaly, pericarditis, and pleuritis. Joint involvement is initially mild or absent, but becomes the more prominent feature of the disease as the patient a...

BACKGROUND In the recent years, musculoskeletal ultrasound (MSUS) has been regarded as especially promising in the assessment of juvenile idiopathic arthritis (JIA), as a reliable method to precisely document and monitor the synovial inflammation process. MAIN CONTENT MSUS is particularly suited for examination of joints in children due to several advantages over other imaging modalities. Som...

Until recently, no uniform and widely accepted criteria for defining remission in juvenile idiopathic arthritis (JIA) were available. In recent years, a set of preliminary criteria for clinical remission in JIA was developed through an international collaborative effort. These criteria enable the classification of patients in the states of inactive disease, clinical remission with medication, a...