Operads were originally defined as V-operads, that is, enriched in a symmetric or braided monoidal category V. The symmetry or braiding in V is required in order to describe the associativity axiom the operads must obey, as well as the associativity that must be a property of the action of an operad on any of its algebras. A sequence of categorical types that filter the category of monoidal cat...

Over 50 allelic variants of cytochrome P450 2D6 (CYP2D6) encoding fully functional, reduced-activity, or nonfunctional proteins have been described. Compared with Caucasians, studies in black populations demonstrate a tendency toward slower CYP2D6 activity, attributed in part to the presence of a variant allele associated with reduced activity, the CYP2D6*17 allele. To investigate the kinetic c...

The joint linear complexity and k error joint linear complexity of an m fold 2n periodic multisequence can be efficiently computed using Modified Games Chan algorithm and Extended Stamp Martin Algorithm respectively. In this paper we derived an algorithm for finding the joint linear complexity of periodic binary multisequence with the help of Modified Games Chan algorithm. Here we derived the m...

Let X denote a compact Riemann surface of genus g. Let K denote the canonical line bundle on X and denote by K n the n-fold tensor power of K. Put dn=dimcH~ Kn)=(2n-1 ) (g -1 )+b ln . At each point P~X, there is a sequence of d, integers 1 = 71 (P) < 72(P) < " " < 7a~(P) < 2 n ( g 1) + 1, called the sequence of n-gaps at P. An integer 7 is an n-gap at P if and only if there exists O~H~ K ~) wit...

BACKGROUND The diffusion of antibiotics through the outer membrane is primarily affected by the porin super family, changes contribute to antibiotic resistance. Recently we demonstrated that the CpxAR two-component signaling system alters the expression of an uncharacterized porin OmpC(KP), to mediate antimicrobial resistance in K. pneumoniae. PRINCIPAL FINDINGS In this study, functional char...

The deacetoxycephalosporin C synthase (DAOCS) from Streptomyces clavuligerus was engineered with the aim of enhancing the conversion of penicillin G into phenylacetyl-7-aminodeacetoxycephalosporanic acid, a precursor of 7-aminodeacetoxycephalosporanic acid, for industrial application. A single round of random mutagenesis followed by the screening of 5,500 clones identified three mutants, G79E, ...

85Sr as radioindicator has been applied to strontium separation selectivity study using cisdicyclohexano-18-crown-6 (DCH18C6) extraction agent and picric acid counter ion with the aim contribute development of a rapid method extraction. The same used for fractionation in chosen soils by application Tessier- BCR sequential procedures. Experimental results have shown, that mentioned system is app...

In this paper, we introduce the concepts of n-fold obstinate pseudo-hoop and n-fold obstinate filter in pseudo-hoops. Then we investigated these notions and proved some properties of them. Also, we discussed the relationship between n-fold obstinate pseudo-hoop and n-fold obstinate filter and other types of n-fold pseudo-hoops and n-fold filters such as n-fold (positive) implicative filter and ...

We construct the full linearisation functor which takes a graded bundle of degree k (a particular kind of graded manifold) and produces a k-fold vector bundle. We fully characterise the image of the full linearisation functor and show that we obtain a subcategory of k-fold vector bundles consisting of symmetric k-fold vector bundles equipped with a family of morphisms indexed by the symmetric g...

UNLABELLED K-Fold is a tool for the automatic prediction of the protein folding kinetic order and rate. The tool is based on a support vector machine (SVM) that was trained on a data set of 63 proteins, whose 3D structure and folding mechanism are known from experiments already described in the literature. The method predicts whether a protein of known atomic structure folds according to a two-...