IFN-kappa is a recently identified type I IFN that exhibits both structural and functional homology with the other type I IFN subclasses. In this study, we have investigated the effect of IFN-kappa on cells of the innate immune system by comparing cytokine release following treatment of human cells with either IFN-kappa or two recombinant IFN subtypes, IFN-beta and IFN-alpha2a. Although IFN-alp...

Ascorbate-enhanced nitric oxide (NO) production in lipopolysaccharide (LPS)- and interferon-gamma (IFN-gamma)-activated macrophage J774.1 cells through the inducible nitric oxide synthase (iNOS) pathway. The iNOS gene was synergistically induced by LPS and IFN-gamma. The inductive mechanism of ascorbate on the iNOS gene was studied by examining the degradation of I kappa B alpha by Western blot...

The murine pre-B leukemic cell line 70Z/3 contains both an unrearranged immunoglobulin kappa-light-chain gene and a functionally rearranged but silent kappa-light-chain gene. Mitogenic stimulation of growing 70Z/3 cells with bacterial lipopolysaccharide (LPS) activates kappa-light-gene transcription and results in a 10- to 20-fold increase in cytoplasmic kappa-light-chain mRNA. The induction of...

AIM To investigate the activation of nuclear factor-kappa B (NF-kappa B) and its function in glucocorticoid-induced Leydig cell apoptosis. METHODS The Leydig cells were isolated from male Sprague-Dawley rats (90 days of age) and were incubated with corticosterone (CORT, glucocorticoid in rat) for 6 h, 12 h and 24 h, respectively. The P65 subunit of NF-kappa B (NF-kappa B/P65) in nuclei and th...

the present research was carried out with the aim of site-specific nitrogen fertilizer management, through aster imagery. a 23 ha corn field in pakdasht town in southern tehran province constituted the research area. plant sampling was carried out simultaneous with the passing by of the satellite sensor over, throughout the farm. a total of 53 pixels were selected through systematic randomized ...

Deep learning methods have been widely applied to visual and acoustic technology. In this paper, we propose an odor labeling convolutional encoder–decoder (OLCE) for identification in machine olfaction. OLCE composes a neural network encoder decoder where the output is constrained labels. An electronic nose was used data collection of gas responses followed by normative experimental procedure. ...

Accurate spatial distribution of grassland degradation indicator species is great significance for monitoring. In order to realize the intelligent remote sensing monitoring task, this paper collects data three desert grassland, namely, constructive species, dominant and companion through UAV hyperspectral platform, proposes a multi-feature fusion (MFF) classification model. addition, vertical c...