INTRODUCTION Odontogenic tumors (OTs) are a heterogeneous group of lesions that are derived from odontogenic apparatus comprised of odontogenic epithelium, ectomesenchyme, and/ or mesenchymal elements. The OTs show marked geographical variation. This study was conducted to analyze the epidemiology and clinicopathological presentation of OTs based on age, sex, and site. MATERIALS AND METHODS T...

Sir, Odontogenic keratocyst (OKC) is known for its pathognomonic features, i.e., aggressiveness and high rates of recurrence, which has been of interest and debate since the first description of this entity by Philipsen in 1956.[1] Recently, the World Health Organization (WHO) working group on odontogenic tumors recommended the term “Keratocystic Odontogenic Tumors” (KCOT) for these lesions to ...

Odontogenic keratocysts (OKCs) are developmental cysts which occur typically in the jawbones. They present more commonly in the posterior mandible of young adults than the maxilla. OKCs have been reclassified under odontogenic tumours in 2005 by the WHO and have since been termed as keratocystic odontogenic tumours (KCOTs). Here we report a case of a recurrent buccal lesion in a 62-year-old man...

Management of the keratocystic odontogenic tumor has been one of the most controversial entities of the maxillofacial surgery. It can become quite large because of its ability for significant expansion, extension into adjacent tissues and rapid growth and also has high reccurence rate as it shows a thin, friable wall, which is often difficult to enucleate from the bone in toto, and have small s...

BACKGROUND Odontogenic cysts are those which arise from the epithelium associated with the development of teeth. Some odontogenic cysts were found to have special biological features that make them distinct from other lesions. This study was conducted to detect the immunoepxression of laminin-1 and Ki-67 in both radicular cysts (RCs) and keratocystic odontogenic tumors (KCOTs) and to examine th...

In 2005, the WHO Working Group considered odontogenic keratocyst (OKC) to be a tumor and recommended the term keratocystic odontogenic tumor (KCOT), separating the lesion from the orthokeratinizing variant, which is now considered an odontogenic cyst. We analyzed the clinicopathological features of KCOTs encountered over a period of 28 years at Meikai University Hospital. The diagnosis was conf...

Squamous cell carcinoma (SCC) arising from epithelial lining of Keratocystic Odonogenic Tumour(KCOT) is very rare with 0.001‐0.002 incidence.[1] Keratin metaplasia leading to epithelial hyperplasia and dysplasia can be one of the mechanisms of malignant changes so, presence of keratinisation in the cyst lining increases the risk of malignancy.[2,3] According to the new histological classificati...

Background: Jaw cysts and cyst-like lesions cause facial deformity, destruction of dental tissues and affect masticatory and phonation functions. These adversely erode patients’ psycho-social status; create low self-esteem and may change one’s facial identity and appearance. Objective: To determine the histopathologic characteristics, variants and demographic pattern of jaw cysts and cyst-like ...

BACKGROUND CD166 is a glycoprotein of an immunoglobulin super family of adhesion molecules that has been associated with aggressive characteristics and high recurrence rate of tumors. Different odontogenic lesions exhibit considerable histological variation and different clinical behavior. In an attempt to clarify the mechanisms underlying this different behavior, the present study investigates...

The aim of the present study was the morphometric evaluation of the epithelial lining and fibrous capsule in histological specimens of keratocystic odontogenic tumors (KOTs) before and after marsupialization. Histological sections from six KOTs that had undergone marsupialization followed by enucleation were photographed. The thickness and features of the capsule and of the epithelial lining of...