IMPORTANCE The loss of vision following Boston Keratoprosthesis (BKPro) surgery due to glaucoma occurs at a high frequency as diagnosis and management of glaucoma after this procedure pose challenges. OBJECTIVE To compare visual outcomes in patients undergoing Boston Keratoprosthesis surgery with and without prior or concurrent glaucoma surgery. DESIGN, SETTING, AND PARTICIPANTS This is a r...

While the 1980s were focused on the solution of large sized ``easy'' knapsack problems (KPs), this decade has brought several new algorithms, which are able to solve ``hard'' large sized instances. We will give an overview of the recent techniques for solving hard KPs, with special emphasis on the addition of cardinality constraints, dynamic programming, and rudimentary divisibility. Computatio...

OBJECT The purpose of this study was to examine the results of using Gamma Knife surgery (GKS) for brain metastases from classically radioresistant malignancies. METHODS The authors retrospectively reviewed the records of 76 patients with melanoma (50 patients), renal cell carcinoma (RCC; 23 patients), or sarcoma (3 patients) who underwent GKS between August 1998 and July 2007. Overall patien...

In this paper, we present the first results of our empirical analysis for the actual use that is made of metadata in Learning Object Repositories, more specifically in the ARIADNE Knowledge Pool System (KPS). We analyze metadata information provided by indexers when they introduce new learning objects into the KPS. This gives a clear indication about their understanding of metadata elements, va...

The implantation of the Boston Keratoprosthesis (KPro) requires a corneal button, which is usually taken from a donor. Scarcity of donor tissue has been a major limiting factor in transplant surgery. Recently, autologous recipient cornea has been reported as support for the KPro. We report the successful use of an ipsilateral failed corneal graft as the carrier tissue for a patient requiring co...

OBJECT The object of this study was to determine the benefit of surgery, radiation, and chemotherapy for patients with glioblastoma multiforme (GBM) and a low Karnofsky Performance Scale (KPS) score. METHODS The authors retrospectively evaluated the records of patients who underwent primary treatment for pathologically confirmed GBM and with a KPS score ≤ 50 on initial evaluation for radiatio...

This study evaluated the efficacy of surgery combined with 125I seed implantation in the treatment of recurrent glioma, and analyzed prognosis-influencing factors. A total of 66 patients with recurrent gliomas in Yidu Central Hospital of Weifang were enrolled in the study from April, 2011 to March, 2014. Patients were randomly divided into a control and an observation group, with 33 patients in...

Age remains the most powerful prognostic factor among glioblastoma (GBM) patients. Half of all patients with GBM are aged 65 years or older at the time of diagnosis, and the incidence rate of GBM in patients aged over 65 years is increasing rapidly. Median survival for elderly GBM patients is less than 6 months and reflects less favorable tumor biologic factors, receipt of less aggressive care,...