In recent years, many private corporations and government organizations have digitized corpuses of legacy paper documents. Often, these organizations hope to take advantage of digital representations to transform costly manual tasks associated with paper archives into less-costly computer-assisted tasks. The most common approach toward automated information extraction is through inverted indexi...

This paper examines the differences between author generated keywords and automatically generated keywords in one area of scientific and technical literature. Using inverse frequency, keywords produced using both methods are examined using a maximum likelihood algorithm. By reducing the scope and size of the corpus of literature examined, this study more closely emulates the information gatheri...

A group of regioisomeric 5-oxo-1,4,5,6,7,8 hexahydroquinoline derivatives possessing a COX-2 SO2Me pharmacophore at the para position of the C-2 or C-4 phenyl ring, in conjunction with a C-4 or C-2 phenyl (4-H) or substituted-phenyl ring (4-F,4-Cl,4-Br,4-OMe,4-Me, 4-NO2), were designed for evaluation as selective cyclooxygenase-2 (COX-2) inhibitors. These target 5-oxo-1,4,5,6,7,8 hexahydroquino...