A 58 year old woman was diagnosed as having polymyalgia rheumatica in 2000. Her blood pressure was slightly raised (140/74 mm Hg). Her past medical history was otherwise unremarkable and her condition stable. She takes 5 mg prednisolone a day, up to six over the counter Panadol tablets (GlaxoSmithKline, Brentwood; 500 mg paracetamol) a day, and Calcichew D3 Forte (Shire, Basingstoke; 1.25 g cal...

3D printing (3DP), or additive manufacturing, has been actively investigated as one of the enabling technologies for impending era personalized medicines. However, existing 3DP do not afford speeds required on-demand production medicines in fast-paced clinical settings. Volumetric is a novel technology that offers rapid speed and overcomes geometric surface quality limitations layer-based vat p...

Sir, Paracetamol poisoning is not a very frequently encountered problem in ouur population, as compared to the incidence in the west. Paracetamol (acetaminophen) is being used as an effective and safer analgesic as compared to non-steroidal anti inflammatory drugs, when administered in therapeutic dose. In contrast to aspirin, it is more likely to cause hepatotoxicity, when taken in larger than...

paracetamol that is known as acetaminophen have the most consume as an analgesic and antipyreticdrug in the world. that is formulated in single compound or mixture at many forms such astablets, syrups, suspensions and drops. the last form is intravenous injections. paracetamol derivedfrom 4-minophenol which is synthesized by acylated the p-acetaminophenol and acetic anhydride.4-aminophenol is t...

A novel electrochemical sensor was constructed by employing zirconium based metal organic framework (NH 2 -UiO-66) and walnut derived carbon (WC) as modified materials for the highly sensitive selective determination of paracetamol (Para) para-aminophenol (PAP). Characterization results texture properties NH -UiO-66/WC nanocomposite revealed that dispersive MOF particles were filled in large po...

Direct compression is the preferred method for the preparation of tablets. Co-processing is the one of the most widely explored and commercially utilized method for the preparation of directly compressible vehicles. The objective of the present study is to prepare and characterize pregelatinized starch-poly vinyl pyrrolidone (PGS-PVP) co-processed excipient and to evaluate its application as di...

Introduction: Patient-controlled analgesia (PCA) with intravenous opioids is a more efficient method to achieve better postoperative analgesia. This study aims describe the use of patient-control in post-hysterectomy patients.
 Case presentation: There were two total hysterectomy patients who used PCA as pain management. Postoperatively, first patient has given paracetamol tablets 500 mg e...

INTRODUCTION The main aim of this study is to determine the pattern of referrals of poisoning to a tertiary university hospital. The information will be used for poison prevention programme planning, and for educating and awareness promoting to the public. MATERIALS AND METHODS All patients (under 21 years of age) admitted to the paediatric wards between January 1997 and December 2002 with a ...

Paracetamol that is known as acetaminophen have the most consume as an analgesic and antipyreticdrug in the world. That is formulated in single compound or mixture at many forms such astablets, syrups, suspensions and drops. The last form is intravenous injections. Paracetamol derivedfrom 4-minophenol which is synthesized by acylated the P-acetaminophenol and acetic anhydride.4-aminophenol is t...

BACKGROUND To determine whether deep dry needling (DDN) of trigger points (TPs) in the lateral pterygoid muscle (LPM) would significantly reduce pain and improve function, compared with methocarbamol/paracetamol medication. MATERIAL AND METHODS Forty-eight patients with chronic myofascial pain located in the LPM were selected and randomly assigned to one of two groups (DDN test group, n=24; d...