Cohesins are required both for the tethering together of sister chromatids (termed cohesion) and subsequent condensation into discrete structures-processes fundamental for faithful chromosome segregation into daughter cells. Differentiating between cohesin roles in cohesion and condensation would provide an important advance in studying chromatin metabolism. Pds5 is a cohesin-associated factor ...

We report on polariton condensation in photonic molecules formed by two coupled micropillars. We show that the condensation process is strongly affected by the interaction with the cloud of uncondensed excitons and thus strongly depends on the exact localization of these excitons within the molecule. Under symmetric excitation conditions, condensation is triggered on both binding and antibindin...

Mesenchymal cell condensation is the initiating event in endochondral bone formation. Cell condensation is followed by differentiation into chondrocytes, which is accompanied by induction of chondrogenic gene expression. Gene mutations involved in chondrogenesis cause chondrodysplasias and other skeletal defects. Using mesenchymal stem cells (MSCs) in an in vitro chondrogenesis assay, we found ...

We performed systematic studies of λ-DNA condensation on mica surfaces induced by alcohol and hexammine cobalt (III) [Co(NH(3))(6)(3+)] using atomic force microscopy (AFM). The critical condensation concentration for [Co(NH(3))(6)(3+)] was found to be about 10 microM; the DNA molecules extended freely on mica when the concentration was below the critical value. The morphology of condensed DNA b...

In this paper, a series of click reaction-based Bodipy derivatives have been synthesized as part preliminary study. Following the characterization four challenger molecules, photophysical properties (absorption, emission, excitation, molar absorption coefficient, quantum yield, etc.) were examined in various organic solvents. The results showed that energy transfer from cores to other moieties ...

the catalytic air oxidation-trimerization of alcohols was carried out with hetropolyacids. in the presence of hetropolyacid formation of cyclotrimers of alcohols and aldol condensation products was observed. the 1,3,5-trioxanes were major and aldol condensation compounds were minor products.

efficient knoevenagel condensation of barbituric acid with different aromatic aldehydes on basic alumina was performed in a conventional microwave over in the absence of solvent.

Zusammenfassung Ausgehend von der methodologischen Fragestellung nach Möglichkeiten und Grenzen „retrospektiver Diagnostik“ wird in diesem Beitrag das Fallbeispiel zeitgenössisch als „dämonische Besessenheit“ interpretierten Erkrankung Maria Eichhorn im Jahre 1599 präsentiert. Die einer handschriftlichen Darstellung eines beteiligten Exorzisten geschilderte Symptomatik wäre moderner psychopatho...