BACKGROUND Treatment of infectious diseases is becoming more challenging with each passing year. This is especially true for infections caused by Pseudomonas aeruginosa, an opportunistic pathogen with the ability to rapidly develop resistance to multiple classes of antibiotics. OBJECTIVES This study was conducted to determine the prevalence of metallo-β-lactamase (MBL)-producing strains among...

metallo β-lactamases (mbls) producing pseudomonas aeruginosa ( p. aeruginosa ) isolates are becoming an escalating global threat. among the antibiotics used to treat infections associated with p. aeruginosa , resistance to carbapenem is a serious therapeutic challenge. the aim of the present study was to detect mbl-producing p. aeruginosa and to evaluate the extracts of urtica. dioica , carum. ...

conclusions multidrug resistance was significantly associated with mbl production in p. aeruginosa. early detection of mbl-producing p. aeruginosa and hospital antibiotic policy prescription helps proper antimicrobial therapy and avoidance of dissemination of these multidrug resistance isolates. background resistant pseudomonas aeruginosa is a serious concern for antimicrobial therapy, as the c...

conclusions the results of this study show that the rate of p. aeruginosa-caused burn wound infections was very high, and many of the isolates were resistant to three or more classes of antimicrobials. such extensive resistance to antimicrobial classes is important because few treatment options remain for patients with burn wound infections. blaimp-producing p. aeruginosa isolates are a rising ...

Background: The opportunistic human pathogen, Pseudomonas aeruginosa, is a critical cause of nosocomial infection with high morbidity and mortality rate. Eradication P. aeruginosa has been troublesome due to its capacity develop strong multidrug resistance (MDR). Objectives: purposes this study were define the pattern antimicrobial sensitivity, typing, prevalence metallo-β-lactamase (MBL) detec...

BACKGROUND Escherichia coli strains mainly fall into four phylogenetic groups (A, B1, B2, and D) and that virulent extra-intestinal strains mainly belong to groups B2 and D. AIM The aim was to determine the association between phylogenetic groups of E. coli causing extraintestinal infections (ExPEC) regarding the site of infection, expression of virulence factors, antimicrobial resistance pat...

Abstract Background Meropenem-vaborbactam (MV) is the first carbapenem/β-lactamase inhibitor combination developed to restore meropenem susceptibility against KPC-producing carbapenem-resistant Enterobacterales(CRE). Vaborbactam (VAB) potently inhibits Ambler class A and C β-lactamases by reversible covalent binding of boronate serine side chains β-lactamases. Resistance MV in non-metallo-β-lac...

background: infectious by pseudomonas aeruginosa has spread worldwide and metallo-beta-lactamases (mbl) are being reported with increasing frequency. the aim of this study was to investigate the antibiotic susceptibility and distribution of blavim and blaimp genes in p. aeruginosa isolates from zanjan province of iran. methods: a total of 70 p. aeruginosa isolates were identified from patients ...

: The emerging multi-drug resistant variants in different clinical isolates is leading to increased morbidity and mortality, due failure treatment. paucity of an accurate data antimicrobial resistance from geographical areas a major setback its control management. aim this study was analyse the occurrence drug organisms samples district Wayanad, also determine most prevalent bacterial pathogens...

Introduction: Skin and soft tissue infections (SSTI’s) are commonly caused by both gram positive and gram negative bacteria. The aim of the study was to investigate the presence of methicillin resistant Staphylococcus aureus (MRSA), Extended Spectrum Beta Lactamase (ESBL), Amp C and Metallo β-lactamase producing gram negative bacilli from clinical isolates obtained from patients attending G.S M...