Hereditary angioedema is an autosomal dominant disease characterized by edema attacks with multiple organ involvement. It is caused by a quantitative or functional deficiency of the C1 inhibitor, which is a member of the serine protease inhibitor family. Hereditary angioedema is unknown to many health professionals and is therefore an underdiagnosed disease. The causes of death from hereditary ...

Vocal cord nodules are benign laryngeal lesions seen in professional voice users. They usually bilateral and thought to occur due submucosal edema hemorrhage, with resultant fibrosis. False occurrences very rare; hence we report a unique case of unilateral right false nodule. A healthy 16-year-old female student presented persistent hoarseness for two years without any history abuse, trauma, in...

Introduction. Chronic edematous-polypous laryngitis, Reinke – Gayek’s edema accounts for 5.5% of all benign diseases the vocal folds. Surgical treatment Gayek disease consists in removing excess mucosa, or “stripping” tearing off a strip mucosa with forceps from fold. The principle laryngeal surgery is to preserve structures fold, obtain flexible vibration muscular-membranous part and mucous me...

Laryngeal cancer metastases are relatively rare and mainly affect the lung. The medullary localization remains exceptional. We report the case of a patient followed for operated laryngeal cancer and whose oncologic control revealed a medullary localization. A patient followed for squamous cell carcinoma of the larynx, treated in 2010 by a partial surgery whose endoscopic control at 5 years reve...

BACKGROUND Sentinel node navigation surgery is gaining popularity in oral cancer. We assessed application of sentinel lymph node navigation surgery to pharyngeal and laryngeal cancers by evaluating the combination of contrast-enhanced ultrasonography and indocyanine green fluorescence in animal models. METHODS This was a prospective, nonrandomized, experimental study in rabbit and swine anima...

Hereditary angioedema is a rare disorder caused by the congenital deficiency or dysfunction of C1 inhibitor. The deficiency results in recurrent episodes of angioedema, mainly involving the mucosa and skin. The most common clinical manifestations are the result of edema in the subcutaneous tissue, abdominal mucosa, and laryngeal tissue. Laryngeal involvement remains the most serious due to the ...

Angioedema related to a deficiency in the C1-inhibitor protein is characterized by its lack of response to therapies including antihistamine, steroids, and epinephrine. In the case of laryngeal edema, mortality rate is approximately 30 percent. The first case of the acquired form of angioedema related to a deficiency in C1-inhibitor was published in 1972. In our paper, we present a case of an a...

Hair dye ingestion is a rare cause of toxicity in Pakistan. Hair dyes contain paraphenylene-diamine (PPD) and a host of other chemicals that can cause rhabdomyolysis, laryngeal edema, severe metabolic acidosis and acute renal failure. Clinical outcomes rely on early recognition, prompt referral, and aggressive supportive treatment. Timely intervention has been shown to improve the outcome. Ther...

A 20-year-old white man sustained a concussion and compression of his chest under a truck during a vehicular accident. The initial chest roentgenogram was significant in that it demonstrated slight widening of the mediastinum, fracture of the right fifth rib, and compression fractures of the lower three thoracic vertebrae. Three days after the accident, the patient's level of consciousness had ...

AIM Injuries due to traffic accidents are frequent in childhood, and they have high mortality and morbidity. Laryngeal injury due to a traffic accident is a rare pathology and might be missed if not suspected. Here we present a laryngeal fracture in a child after a blunt chest trauma during a traffic accident that presented with pneumomediastinum and pneumothorax. CASE A 14-year-old girl was ...