conclusions the association of the 1st trimester high hb and hct with preeclampsia was revealed in this study, therefore it could be used as a prediction factor for early preeclampsia diagnosis. results preeclampsia incidence was 5.1% in our study. mean hb was 12.38 ± 1.69 g/dl in the preeclampsia group and 11.8 ± 1.18 in the non-preeclampsia group, and mean hct was 37.74 ± 5.15% in the preecla...

Although research on the neurobiological foundation of social affiliation has implicated the neuropeptide oxytocin in processes of maternal bonding in mammals, there is little evidence to support such links in humans. Plasma oxytocin and cortisol of 62 pregnant women were sampled during the first trimester, last trimester, and first postpartum month. Oxytocin was assayed using enzyme immunoassa...

Congenital heart defects (CHDs) are the leading cause of infant mortality due to birth defects. In the last 15 years, with the shift in screening for aneuploidies to the first trimester, extensive research has concentrated on early screening and detection of CHDs. Early detailed assessment of the fetal heart requires a high level of expertise in early anomaly scanning and fetal echocardiography...

Appropriate diagnosis and treatment of hyperthyroidism during pregnancy are of outmost importance, because hyperthyroidism has major adverse impact on both mother and fetus. Since data on the management of thyroid dysfunction during pregnancy is rapidly evolving, two guidelines have been developed by the American Thyroid Association and the Endocrine society in the last 2 years. We compare here...

Pregnancy in the setting of pulmonary hypertension and Eisenmenger physiology is associated with a substantial maternal and fetal risk. Such patients are advised against pregnancy. We report a case of a woman with an Eisenmenger atrial septal defect diagnosed during the last trimester of pregnancy. On presentation, she was critically ill and there was evidence of fetal distress. She was emergen...

Prenatal diagnosis pf chromosomal abnormalities can be accurately made by cytogenetic studies of samples obtained from invasive procedures, such as amniocentesis or chorionic villus sampling. Because these procedures are associated with a risk of miscarriage, the common approach is to perform non-invasive test to define an individual woman's risk of having a chromosomal abnormal pregnancy. Scre...

Osteopenia of prematurity and neonatal metabolic bone disease are terms used to describe the reduced skeletal mineralization seen in preterm babies at term as compared with those who have remained in utero. During the last trimester of pregnancy there is a rapid accretion of calcium and phosphorus due to active transport across the placenta(l). The osteopenia makes the preterm newborn more susc...

The matching criteria were gestation (using an ultrasound crown–rump length or biparietal diameter measurement), duration of storage, and centre. Screening performance of the individual markers and combinations of markers together with maternal age was assessed using standard methods. In addition pairs of first and second trimester serum samples from 600 controls were tested to secure a larger ...

Rhesus monkeys (Macaca mulatta) were immunized with purified P fimbriae from Escherichia coli during the last trimester of pregnancy. Infants born of these mothers were compared with those from nonimmunized rhesus mothers. A delay in the onset of renal disease after bladder infection showed protection from passive immunization. This was associated with a high antibody titer in serum. In additio...

objective: to study the pregnancy outcomes in first trimester vaginal bleeding. materials and methods: this cross sectional study was done on 60 pregnant women with first trimester vaginal bleeding referring to university hospitals affiliated to islamic azad university, tehran, iran. all women were evaluated for the outcomes including abortion, preterm rapture of membranes, preterm labor, secon...