The spindle assembly checkpoint (SAC) blocks entry into anaphase until all chromosomes have stably attached to the mitotic spindle through their kinetochores. The checkpoint signal originates from unattached kinetochores, where there is an enrichment of SAC proteins. Whether the enrichment of all SAC proteins is crucial for SAC signaling is unclear. Here, we provide evidence that, in fission ye...

S-Allyl-L-cysteine (SAC), a component of garlic and a metabolite of allyl halides, is a known substrate for multiple flavin-containing monooxygenases (FMOs). In the current study, we characterize the in vivo SAC metabolism by investigating the presence of SAC, N-acetyl-S-allyl-L-cysteine (NASAC), and their corresponding sulfoxides in the urine of rats given SAC (200 or 400 mg/kg i.p.). In some ...

Abstract Introduction An internal hernia occurs when part of the bowel protrudes through a mesenteric or peritoneal orifice which could be either normally present acquired. These hernias usually represent challenge to diagnose. Of natural anatomical orifices is Foramen Winslow caecum and ascending colon herniate. Case Report 85-year-old gentleman presented with one-day history abdominal pain. H...

CONTEXT The presence of a combined serous cystadenoma and pancreatic endocrine neoplasm is a distinct clinicopathological entity rather than the incidental concurrence of two separate entities. CASE REPORT We report the case of a 52-year-old woman admitted to our hospital who had suffered from epigastric pain, nausea and vomiting for 4 months. Imaging techniques showed an irregular mass havin...

OBJECTIVES (1) To study the prevalence and characteristics of large endolymphatic sac internal compartments on thin-section T2- and T2*-weighted magnetic resonance imaging, and to relate these to other large endolymphatic sac magnetic resonance imaging features, and (2) to correlate the compartment imaging features, endolymphatic sac size and labyrinthine anomalies with the patients' clinical a...

FKLF-2, a novel Krüppel-type zinc finger protein, was cloned from murine yolk sac. The deduced polypeptide sequence of 289 amino acids has 3 contiguous zinc fingers at the near carboxyl-terminal end, an amino-terminal domain characterized by its high content of alanine and proline residues and a carboxyl-terminal domain rich in serine residues. By Northern blot hybridization, the human homologu...

To provide an effective method of green aquaculture, the photocatalysts CuO/ZrO2/CB/coal-tar-pitch-SAC, which have visible light sterilization capacity, were successfully fabricated by coating ZrO2 and CuO on surface CB/coal-tar-pitch-SAC. The structures synthesized CuO/ZrO2/CB/coal-tar-pitch-SAC investigated XRD, XPS SEM measurements in detail. It was observed that materials possess obvious he...

Introduction: Dacryocystorhinostomy (DCR), a popular surgical procedure, has been performed using an endoscopic approach over recent years. Excellent anatomical knowledge is required for this endoscopic surgical approach. This study was performed in order to better evaluate the anatomical features of the lacrimal apparatus from cadavers in the Isfahan forensic center as a sample of the Iranian ...